Search

Displaying results 841 - 850 of 4626 in total
  1. Pathway

    Isoflurophate Action Pathway (new)

    smpdb.ca/view/SMP0126686
    Drug action

    Isoflurophate is a cholinesterase inhibitor used to treat glaucoma, as it acts as a powerful miotic agent constricting the pupil and causing the aqueous fluid to flow out and relieve pressure. It acts by irreversibly binding to acetylcho...

    Drugs: Choline · Isoflurophate · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  2. Pathway

    Demecarium Action Pathway (new)

    smpdb.ca/view/SMP0126687
    Drug action

    Demecarium is a cholinesterase inhibitor used in the treatment of glaucoma, acting as an indirect parasympathomimetic agent by increasing acetylcholine levels in the synaptic cleft. The mechanism of action is demecarium the drug acts on ...

    Drugs: Choline · Demecarium · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  3. Pathway

    Rivastigmine Action Pathway (new)

    smpdb.ca/view/SMP0126688
    Drug action

    Rivastigmine is a cholinesterase inhibitor used in the treatment of symptoms of dementia in Alzheimer's and Parkinson's. The drug reversible binds to and inhibits acetylcholinesterase and cholinesterase which stops the breakdown of acety...

    Drugs: Choline · Rivastigmine · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  4. Pathway

    Echothiophate Action Pathway

    smpdb.ca/view/SMP0126704
    Drug action

    Echothiophate also known as phospholine iodide is an acetylcholinesterase inhibitor, used in the treatment of glaucoma in order to increase the drainage of intraocular fluid. It is administered via eye drops and acts on acetylcholinester...

    Drugs: Choline · Echothiophate · Calcium · Magnesium cation · Acetylcholine · Acetic acid
    Enzymes: High affinity choline transporter 1
  5. Pathway

    Phenserine Action Pathway

    smpdb.ca/view/SMP0126724
    Drug action

    Phenserine is a next-generation acetylcholinesterase, used to treat dementia. It acts as a highly selective reversible acetylcholinesterase inhibitor, which is known to increase acetylcholine levels in the synaptic cleft and enhance the ...

    Drugs: Choline · Calcium · Magnesium cation · Acetylcholine · Acetic acid · Phenserine
    Enzymes: High affinity choline transporter 1
  6. Drug

    CX-046684

    go.drugbank.com/drugs/DB19414
    Approved

    CX-046684 is a COVID-19 mRNA vaccine encoding the pre-fusion stabilized Spike glycoprotein (S) of the SARS-CoV-2 Omicron variant lineage KP.2. It is the active ingredient of the 2024-2025 formulation of Moderna's Spikevax vaccine.

  7. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle during depolarization. … Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class.

  8. Drug

    Eletriptan

    go.drugbank.com/drugs/DB00216
    ApprovedInvestigational

    Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.

  9. Drug

    Prednisolone acetate

    go.drugbank.com/drugs/DB15566
    ApprovedInvestigationalVet approved

    Prednisolone acetate is a [prednisolone] molecule bound to an acetate functional group by an ester bond.[L9449] Prednisolone acetate was granted FDA approval in 1955.[L9449]

  10. Drug

    Tedizolid phosphate

    go.drugbank.com/drugs/DB09042
    Approved

    [L11232, A199086, A199050] Tedizolid was approved by the FDA on June 20, 2014, for sale by Cubist Pharmaceuticals as tedizolid phosphate (SIVEXTRO®).