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Displaying results 841 - 850 of 10000 in total
  1. Indication

    Severe Haemophilia A Without Inhibitor

    go.drugbank.com/conditions/DBCOND0173564
    Drugs: Concizumab
    Synonyms: Severe Haemophilia A Without Inhibitor, Severe hemophilia A without inhibitor
  2. Indication

    Influenza A Virus Infection

    go.drugbank.com/conditions/DBCOND0036858
    Drugs: Amantadine · Influenza A virus A/Hong Kong/4801/2014 (H3N2) recombinant hemagglutinin antigen · Influenza A virus A/Hong Kong/4801/2014 X-263B (H3N2) antigen (propiolactone inactivated) · Influenza A virus A/Michigan/45/2015 (H1N1) recombinant hemagglutinin antigen · Influenza A virus A/New caledonia/71/2014 (H3N2) live (attenuated) antigen · Influenza A virus A/Singapore/GP1908/2015 IVR-180A (H1N1) antigen (propiolactone inactivated) +3 more
    Synonyms: Influenza A, Influenza A H1N1
  3. Indication

    Influenza A, Influenza B

    go.drugbank.com/conditions/DBCOND0051432
    Drugs: Oseltamivir
    Synonyms: Influenza A,B, Influenza A, Influenza B
  4. Drug

    Carmustine

    go.drugbank.com/drugs/DB00262
    ApprovedInvestigational

    A cell-cycle phase nonspecific alkylating antineoplastic agent. It is used in the treatment of brain tumors and various other malignant neoplasms. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p462) This substance may reasonably be anticipated to be a carcinogen according to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: N,N'-Bis(2-chloroethyl)-N-nitrosourea
  5. Drug

    Rumex crispus whole

    go.drugbank.com/drugs/DB14267
    Approved

    Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Products: JEUNCELL a drug for atopic dermatitis
  6. Drug

    Horseradish

    go.drugbank.com/drugs/DB10674
    Approved

    Horseradish allergenic extract is used in allergenic testing.

    Products: Nwk A-FV
  7. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.

    Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamide, [(1R)-3-methyl-1-({(2S)-3-phenyl-2-[(pyrazin-2-ylcarbonyl)amino]propanoyl}amino)butyl]boronic acidCategories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index
  8. Target

    Coagulation factor XIII A chain

    go.drugbank.com/bio_entities/BE0000004
    TargetEnzymeHumans

    Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot

    Polypeptides: Coagulation factor XIII A chainSynonyms: Transglutaminase A chain, Protein-glutamine gamma-glutamyltransferase A chain
  9. Target

    L-lactate dehydrogenase A chain

    go.drugbank.com/bio_entities/BE0000425
    TargetHumans

    Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)

    Polypeptides: L-lactate dehydrogenase A chainSynonyms: LDH-A
  10. Target

    DNA topoisomerase 4 subunit A

    go.drugbank.com/bio_entities/BE0000429
    TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

    Performs the decatenation events required during the replication of a circular DNA molecule.

    Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit A