Search
Dexpanthenol
go.drugbank.com/drugs/DB09357ApprovedInvestigationalDue to its good penetration and high local concentrations, dexpanthanol is used in many topical products, such as ointments and lotions for treatment of dermatological conditions to relieve itching or … Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.
Mixtures: Supravite 10ml Ampoule, Somarexin and C 1000Categories: Vitamin D and Analogues, Alimentary Tract and MetabolismDuloxetine
go.drugbank.com/drugs/DB00476ApprovedInvestigationalDuloxetine is a dual serotonin and norepinephrine reuptake inhibitor.[label] It was originally discovered in 1993 and developed by Eli Lilly and Company as LY248686. … Duloxetine continues to be investigated for the treatment of pain in cancer, surgery, and more.
Categories: Serotonin and Noradrenaline Reuptake Inhibitors, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: (3S)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propan-1-aminePlantago seed
go.drugbank.com/drugs/DB11097ApprovedInvestigationalPlatango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements.
Categories: Herbs and Natural ProductsProducts: Up and Up Fiber Therapy, up and up fiber therapy Natural FiberVon Willebrand factor human
go.drugbank.com/drugs/DB13133ApprovedInvestigationalThe human vWF is used to manage and control bleeding episodes in patients with von Willebrand disease and hemophilia A. It was first approved by the FDA in 2015. … It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII).
Mixtures: Haemate P Powder and solvent for solution for injection or infusion, Wilate 500, 500 IU VWF/500 IU FVIII, Powder and Solvent for Solution for InjectionCategories: Blood and Blood Forming Organs, Amino Acids, Peptides, and ProteinsFluvastatin
go.drugbank.com/drugs/DB01095ApprovedInvestigationalFluvastatin belongs to a class of medications called statins and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. … Fluvastatin is a racemate comprising equimolar amounts of (3R,5S)- and (3S,5R)-fluvastatin.
Products: Lescol 20mg, FLUVASTATIN HEXAL 20MGRofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnCytochrome P450 1A2, Cytochrome P450 3A4, Cytochrome P450 2C9, Cytochrome P450 2C8, and Prostaglandin G/H synthase 1 are known to metabolize rofecoxib. … Rofecoxib has a half-life of 17 hours and its mean oral bioavailability at therapeutically recommended doses of 125, 25, and 50 mg is approximately 93%.
Categories: Antiinflammatory and Antirheumatic Products, Non-Steroids, Antiinflammatory and Antirheumatic ProductsProducts: Vioxx Tab 25mg, ROFECOXIB 25MGPiperazine
go.drugbank.com/drugs/DB00592ApprovedVet approvedWithdrawnOutside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. … Piperazine compounds mediate their anthelmintic action by generally paralyzing parasites, allowing the host body to easily remove or expel the invading organism.
Categories: Piperazine and Derivatives, Antiparasitic Products, Insecticides and RepellentsProducts: Versol 100mg, NEO ULTRAXONFusidic acid
go.drugbank.com/drugs/DB02703ApprovedInvestigationalIt is often used topically in creams and eyedrops but is available in systemic formulations including tablets and injections. … An antibiotic isolated from the fermentation broth of Fusidium coccineum. (From Merck Index, 11th ed) It acts by inhibiting translocation during protein synthesis.
Mixtures: BACTAFUZ-B Fusidic Acid and Betamethasone Valerate Cream, ACELER-COProducts: FUCIDIN 20MG/G CREME, FUCIDIN 20MG/G SALBETibolone
go.drugbank.com/drugs/DB09070ApprovedInvestigationalTibolone (Livial, Org OD 14), produced by Organon (West Orange, NJ), is a synthetic steroid that possesses estrogenic, androgenic and progestogenic properties. … Tibolone is approved in 90 countries to manage menopausal symptoms and in 45 countries to prevent the development of osteoporosis [L1876].
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemSynonyms: 17-hydroxy-7alpha-methyl-19-nor-17alpha-pregn-5(10)-en-20-yn-3-oneCrizotinib
go.drugbank.com/drugs/DB08865ApprovedInvestigational[A250785] Crizotinib was approved by the FDA in 2011, and its use is accompanied by FDA-approved tests used to detect ALK and ROS1 rearrangements.[L42460] … Second- and third-generation ALK-tyrosine kinase-inhibitors have overcome many of the pharmacodynamic and genetic resistance mechanisms crizotinib is prone to.
Categories: Antineoplastic and Immunomodulating AgentsProducts: Xalkori Capsules 250mg, Xalkori 250mg Hard Capsules