Search
5-hydroxytryptamine receptor 3
go.drugbank.com/bio_entities/BE0010272TargetHumansForms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons
Polypeptides: 5-hydroxytryptamine receptor 3A, 5-hydroxytryptamine receptor 3BSynonyms: Serotonin receptor 3A, Serotonin receptor 3BActivin receptor type-2B
go.drugbank.com/bio_entities/BE0010524TargetHumansActivin binds to type-2 receptor at the plasma membrane and activates its serine-threonine kinase. The activated receptor type-2 then phosphorylates and activates the type-1 receptor. … Transmembrane serine/threonine kinase activin type-2 receptor forming an activin receptor complex with activin type-1 serine/threonine kinase receptors (ACVR1, ACVR1B or ACVR1c).
Polypeptides: Activin receptor type-2BSynonyms: Activin receptor type IIBGalanin receptor type 2
go.drugbank.com/bio_entities/BE0011498TargetHumansReceptor for the hormone galanin and GALP. Receptor for the hormone spexin-1 (PubMed:24517231). … The activity of this receptor is mediated by G proteins that activate the phospholipase C/protein kinase C pathway (via G(q)) and that inhibit adenylyl cyclase (via G(i))
Polypeptides: Galanin receptor type 2Function: galanin receptor activitySigma intracellular receptor 2
go.drugbank.com/bio_entities/BE0015084TargetHumansSigma-2 receptor implicated in the regulation of multiple cellular processes, including cholesterol biosynthesis and trafficking, membrane trafficking, autophagy, lipid membrane-associated protein trafficking
Polypeptides: Sigma intracellular receptor 2Synonyms: Sigma2 receptor, Sigma-2 receptorChemerin-like receptor 1
go.drugbank.com/bio_entities/BE0019036TargetHumansReceptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1.
Polypeptides: Chemerin-like receptor 1Synonyms: Chemokine-like receptor 1, G protein-coupled receptor DEZAbiprubart
go.drugbank.com/drugs/DB19333InvestigationalAbiprubart is being evaluated for its efficacy and safety in participants with Sjögren's Disease in clinical trial NCT06531395
Synonyms: Immunoglobulin G4-kappa, anti-[Homo sapiens CD40 (TNFRSF5, tumor necrosis factor receptor (TNFR) superfamily member 5, p50)], humanized monoclonal antibodyTechnetium Tc-99m pertechnetate
go.drugbank.com/drugs/DB09314ApprovedInvestigationalHowever, in contrast to the iodide ion, the pertechnetate ion is released unchanged from the thyroid gland. … This is normally supplied in a hospital setting through the use of a technetium-99m generator, whereby technetium exits the generator in the form of the pertechnetate ion, TcO4−, which can be extracted
Synonyms: Technetium Tc 99m Pertechnetate, Technetium Tc-99m pertechnetateSalts: Technetium Tc-99m sodium pertechnetateEndothelin receptor type B
go.drugbank.com/bio_entities/BE0000043TargetHumansNon-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
Polypeptides: Endothelin receptor type BSynonyms: Endothelin receptor non-selective typeMuscarinic acetylcholine receptor M3
go.drugbank.com/bio_entities/BE0000045TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M3Muscarinic acetylcholine receptor M1
go.drugbank.com/bio_entities/BE0000092TargetHumansThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action
Polypeptides: Muscarinic acetylcholine receptor M1Function: G protein-coupled acetylcholine receptor activity