Search
Saquinavir
go.drugbank.com/drugs/DB01232ApprovedInvestigationalIn 1995 it became the first protease inhibitor approved by the FDA, followed shortly by ritonavir in 1996, and remains in clinical use today due to a relatively benign adverse effect profile as compared … Saquinavir is an HIV-1 protease inhibitor used in combination with [ritonavir] and other antiretrovirals for the treatment of human immunodeficiency virus-1 (HIV-1) infection.
Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsProducts: BIOQUINAVIR ® CAPSULAS 200MGPaliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalIt has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. … Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 9-hydroxyrisperidoneBismuth subsalicylate
go.drugbank.com/drugs/DB01294ApprovedVet approved[L32318] Bismuth subsalicylate is a component of HELIDAC Therapy (bismuth subsalicylate, [metronidazole], and [tetracycline]), which is a treatment regimen indicated for the eradication of _H. pylori_ … [A230728] It is an active ingredient found in Pepto-Bismol, a common over-the-counter medication that is used to temporarily treat discomforts of the stomach and gastrointestinal tract.
Synonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-oneProducts: BISMUCAR®, BISLAKSO ®St. John's Wort
go.drugbank.com/drugs/DB01323ApprovedNutraceuticalMixtures: S. R. FormulaCategories: Complex Mixtures, P-glycoprotein inducersPotassium cation
go.drugbank.com/drugs/DB01345ApprovedThe cell membrane potential created by potassium and sodium ions allows the cell generate an action potential—a "spike" of electrical discharge. … The concentration differences of these charged particles causes a difference in electric potential between the inside and outside of cells, known as the membrane potential.
Mixtures: Telom-X-geneSynonyms: potassium(1+), potassium(1+) ionLithium cation
go.drugbank.com/drugs/DB01356ApprovedInvestigationalWithdrawnThe active principle in these salts is the lithium ion Li+, which having a smaller diameter, can easily displace K+ and Na+ and even Ca+2, in spite of its greater charge, occupying their sites in several … It is also sometimes prescribed as a preventive treatment for migraine disease and cluster headaches.
Ephedra sinica root
go.drugbank.com/drugs/DB01363ApprovedNutraceuticalThe sale of ephedra-containing supplements intended to increase muscle weight or promote weight loss was banned in the United States in 2004 due to the risk for adverse effects and a lack of evidence for
Mixtures: Miller's Formula No. 1Categories: Complex Mixtures, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesTiotropium
go.drugbank.com/drugs/DB01409ApprovedInvestigationalTiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma.
Mixtures: SPIOLTO®RESPIMAT®, SPIOLTO®RESPIMAT®Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingThiothixene
go.drugbank.com/drugs/DB01623ApprovedA thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingTromethamine
go.drugbank.com/drugs/DB03754ApprovedInvestigationalIt is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used
Categories: Compounds used in a research, industrial, or household settingSynonyms: 2-Amino-2-(hydroxymethyl)-1,3-propanediol