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Displaying results 8531 - 8540 of 10000 in total
  1. Drug

    Tempol

    go.drugbank.com/drugs/DB12449
    Investigational

    Tempol has been used in trials studying the treatment of Anal Cancer.

    Synonyms: 1-PIPERIDINYLOXY,4-HYDROXY-2,2,6,6-TETRAMETHYL-, 4-HYDROXY-2,2,6,6-TETRAMETHYL-1-PIPERIDINYLOXYCategories: Compounds used in a research, industrial, or household setting
  2. Drug

    Rimegepant

    go.drugbank.com/drugs/DB12457
    ApprovedInvestigational

    Rimegepant is an oral antagonist of the CGRP receptor developed by Biohaven Pharmaceuticals. … [A189207] Antagonism of the CGRP pathway has become an attractive target for migraine therapy as, unlike the triptans, oral CGRP antagonists have no observed vasoconstrictive properties and are therefore

    Categories: MATE 1 Inhibitors, P-glycoprotein substrates
  3. Drug

    GLPG-0492

    go.drugbank.com/drugs/DB12461
    Investigational

    Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Semagacestat

    go.drugbank.com/drugs/DB12463
    Investigational

    Semagacestat has been used in trials studying the treatment of Alzheimer Disease.

    Categories: Heterocyclic Compounds, 1-Ring
  5. Drug

    Ketanserin

    go.drugbank.com/drugs/DB12465
    Investigational

    Ketanserin has been investigated for the treatment of Septic Shock, Severe Sepsis, and Diabetic Foot Ulcer.

    Mixtures: SUFREXAL PCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Taurolidine

    go.drugbank.com/drugs/DB12473
    ApprovedInvestigational

    Taurolidine is an antimicrobial used for the prevention of catheter-related infections. It is a derivative of the amino acid [taurine]. … It was first synthesized in the 1970s and was originally used as a prophylactic against intraperitoneal bacterial infections in patients with peritonitis.

    Categories: Heterocyclic Compounds, 1-RingProducts: Taurolin (Taurolidin "Geistlich") 2% - Instillationslösung
  7. Drug

    Tetrahydrouridine

    go.drugbank.com/drugs/DB12484
    Investigational

    Tetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Fasiglifam

    go.drugbank.com/drugs/DB12491
    Investigational

    Fasiglifam has been used in trials studying the treatment of Chronic Kidney Disease, Type 2 Diabetes Mellitus, and Diabetes Mellitus, Type 2.

    Categories: Heterocyclic Compounds, 2-Ring
  9. Drug

    Piritramide

    go.drugbank.com/drugs/DB12492
    ApprovedWithdrawn

    Piritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Clascoterone

    go.drugbank.com/drugs/DB12499
    ApprovedInvestigational

    [L15621] Clascoterone is also being investigated as a novel treatment for androgenetic alopecia.[A218766] … Clascoterone (cortexolone 17α-propionate, CB-03-01) is a novel antagonist of androgen receptors. It binds to androgen receptors with high affinity.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2B6 Inhibitors