Search

Displaying results 851 - 860 of 1809 in total
  1. Target

    Taste receptor type 2 member 4

    go.drugbank.com/bio_entities/BE0020472
    TargetHumans

    Gustducin-coupled receptor for denatonium and N(6)-propyl-2-thiouracil implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract.

    Polypeptides: Taste receptor type 2 member 4Function: bitter taste receptor activity
  2. Target

    Short transient receptor potential channel 6

    go.drugbank.com/bio_entities/BE0020965
    TargetHumans

    Mediates calcium entry following G(q)-coupled receptor or receptor tyrosine kinase activation, which triggers phospholipase C (PLC)-mediated hydrolysis of phosphatidylinositides and production of diacylglycerol … Mediates depolarization of intrinsically photosensitive retinal ganglion cells (ipRGCs) in response to light-induced melanopsin (OPN4)-mediated phototransduction via G(q)-PLC signaling, likely by forming

    Polypeptides: Short transient receptor potential channel 6Synonyms: Transient receptor protein 6
  3. Target

    Neuropeptide Y receptor type 4-2

    go.drugbank.com/bio_entities/BE0024014
    TargetHumans

    G protein-coupled receptor for PPY/pancreatic polypeptide/PP, NPY/neuropeptide Y and PYY/peptide YY that is negatively coupled to cAMP.

    Polypeptides: Neuropeptide Y receptor type 4-2Function: pancreatic polypeptide receptor activity
  4. Target

    T cell receptor gamma variable 9

    go.drugbank.com/bio_entities/BE0025222
    TargetHumans

    V region of the variable domain of T cell receptor (TR) gamma chain that participates in the antigen recognition (PubMed:24600447).

    Polypeptides: T cell receptor gamma variable 9
  5. Drug

    Zinc oxide

    go.drugbank.com/drugs/DB09321
    ApprovedInvestigational

    Zinc oxide is an inorganic compound used in a number of manufacturing processes. It can be found in rubbers, plastics, ceramics, glass, cement, lubricants, paints, ointments, adhesives, sealants, pigments, foods, batteries, ferrites, fir...

    Mixtures: Viva CT Prenatal, Vita SoluballProducts: BOA VIDA Calvida, FITGLOW Vita Shield Hyaluronic Primer SPF-30
  6. Drug

    Motixafortide

    go.drugbank.com/drugs/DB14939
    ApprovedInvestigational

    L48116] Hematopoietic stem cell transplantation (HSCT) is commonly employed in the context of hematologic cancers - high-dose chemotherapy regimens destroy cancerous blood cells, which are then replaced via … [L48136] Similar in mechanism to the previously approved [plerixafor], motixafortide is an inhibitor of C-X-C Motif Chemokine Receptor 4 (CXCR4), a protein that helps to anchor stem cells to bone marrow

  7. Drug

    Aluminum zirconium pentachlorohydrate

    go.drugbank.com/drugs/DB11147
    Approved

    Its main mechanism of action is through blocking the pores via formation of polymer complex and preventing sweat from leaving the body.

  8. Target

    Vascular endothelial growth factor receptor 3

    go.drugbank.com/bio_entities/BE0000023
    TargetHumans

    The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. … Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular

    Polypeptides: Vascular endothelial growth factor receptor 3Synonyms: Tyrosine-protein kinase receptor FLT4
  9. Target

    Receptor-type tyrosine-protein kinase FLT3

    go.drugbank.com/bio_entities/BE0000147
    TargetHumans

    Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways … Tyrosine-protein kinase that acts as a cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells.

    Polypeptides: Receptor-type tyrosine-protein kinase FLT3Synonyms: FL cytokine receptor
  10. Target

    Sigma non-opioid intracellular receptor 1

    go.drugbank.com/bio_entities/BE0000290
    TargetHumans

    Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the...

    Polypeptides: Sigma non-opioid intracellular receptor 1Synonyms: Sigma 1-type opioid receptor, Sigma non-opioid intracellular receptor 1