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Interferon alfa
go.drugbank.com/drugs/DB05258ApprovedInvestigationalWithdrawnInterferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. … Multiferon consists of the 6 major subtypes are IFN-α1, IFN-α2, IFN-α8, IFN-α10, IFN-α14 and IFN-α21. Of these, IFN-α2 and IFN-α14 are glycosylated.
Categories: Interferon Type I, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: HuIFN-alpha-Le, IFN-αReviparin
go.drugbank.com/drugs/DB09259ApprovedReviparin is a low molecular weight heparin which seems to have a better safety profile than unfractionated heparin. … Reviparin has a molecular weight of 3.9 kDa.[A32021] It was developed by Abbott laboratories and in 2009, reviparin presented an orphan drug designation by the FDA.[L1469]
Products: CLIVARIN 5726 IE A XA/ML, CLIVARODI 17178 A XA/MLLanreotide
go.drugbank.com/drugs/DB06791ApprovedInvestigationalThis drug is a long-acting analog of the drug somatostatin, a growth hormone inhibitor. … Lanreotide is a drug employed in the management of acromegaly (a hormonal condition caused by excess growth hormone) in addition to symptoms caused by neuroendocrine tumors, especially carcinoid syndrome
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 InhibitorsProducts: Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 120 mg, Somatuline Autogel Prolonged Release Solution for Injection in a Pre-filled Syringe 60 mgHydrocortisone succinate
go.drugbank.com/drugs/DB14545ApprovedInvestigationalCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InducersProducts: A-hydrocort, A-hydrocort Inj 250mg/2mlNitazoxanide
go.drugbank.com/drugs/DB00507ApprovedInvestigationalVet approvedNitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and … Recently, this drug has been studied as a broad-spectrum antiviral agent due to its ability to inhibit the replication of several RNA and DNA viruses [A31977].
Categories: Heterocyclic Compounds, 1-RingProducts: N/a, XINPA 2 % POLVO PARA RECONSTITUIR A SUSPENSIÓN ORALCoagulation factor XIII A chain
go.drugbank.com/bio_entities/BE0000004TargetEnzymeHumansFactor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot
Polypeptides: Coagulation factor XIII A chainSynonyms: Transglutaminase A chain, Protein-glutamine gamma-glutamyltransferase A chainL-lactate dehydrogenase A chain
go.drugbank.com/bio_entities/BE0000425TargetHumansInterconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+)
Polypeptides: L-lactate dehydrogenase A chainSynonyms: LDH-ADNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0000429TargetHaemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)Performs the decatenation events required during the replication of a circular DNA molecule.
Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit ADNA topoisomerase 4 subunit A
go.drugbank.com/bio_entities/BE0000798TargetEscherichia coli (strain K12)MukB stimulates the relaxation activity of topoisomerase IV and also has a modest effect on decatenation (PubMed:20921377).
Polypeptides: DNA topoisomerase 4 subunit ASynonyms: Topoisomerase IV subunit ARibose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001628TargetShigella flexneriCatalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase A