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Displaying results 851 - 860 of 10000 in total
  1. Target

    Coenzyme A biosynthesis bifunctional protein CoaBC

    go.drugbank.com/bio_entities/BE0002020
    TargetEscherichia coli (strain K12)

    Catalyzes two sequential steps in the biosynthesis of coenzyme A.

    Polypeptides: Coenzyme A biosynthesis bifunctional protein CoaBC
  2. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  3. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0004194
    TargetEscherichia coli (strain K12)

    PPIases accelerate the folding of proteins (Probable). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2190212).

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  4. Target

    Platelet-derived growth factor subunit A

    go.drugbank.com/bio_entities/BE0010246
    TargetHumans

    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum ...

    Polypeptides: Platelet-derived growth factor subunit ASynonyms: PDGF subunit A, Platelet-derived growth factor A chain
  5. Drug

    Oxacillin

    go.drugbank.com/drugs/DB00713
    ApprovedInvestigational

    An antibiotic similar to [flucloxacillin] used in resistant staphylococci infections.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-3,3-dimethyl-6-{[(5-methyl-3-phenylisoxazol-4-yl)carbonyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (5-methyl-3-phenyl-4-isoxazolyl)penicillin
  6. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    If left untreated, the body starts to break down fat, instead of glucose, for energy which results in a build-up of ketone acids in the blood and a syndrome called ketoacidosis, which is a life-threatening … Insulin glulisine is a short-acting form of insulin used for the treatment of hyperglycemia caused by Type 1 and Type 2 Diabetes.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen, APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN
  7. Indication

    Bacterial infection due to streptococcus, group A

    go.drugbank.com/conditions/DBCOND0025102
    Drugs: Clavulanic acid
    Synonyms: Bacterial infection due to streptococcus, group A
  8. Indication

    Bleeding caused by Hemophilia A Without Inhibitor

    go.drugbank.com/conditions/DBCOND0170627
    Drugs: Fitusiran · Marstacimab
    Synonyms: Bleeding caused by Hemophilia A Without Inhibitor
  9. Indication

    Proteinuria caused by Primary Immunoglobulin A Nephropathy

    go.drugbank.com/conditions/DBCOND0168683
    Drugs: Sibeprenlimab
    Synonyms: Proteinuria caused by Primary Immunoglobulin A Nephropathy
  10. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: (RS)-1-(4-tert-butylphenyl)-4-{4-[hydroxy(diphenyl)methyl]piperidin-1-yl}-butan-1-ol