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Tridecactide
go.drugbank.com/drugs/DB15687InvestigationalTridecactide, also known as alpha-corticotropin 1-13, is a deacetylated and deaminated alpha-melanocyte stimulating hormone, which may have antipyretic, anti-inflammatory, and antimicrobial effects.
Synonyms: alpha-1-13-corticotropin, humanAzoximer bromide
go.drugbank.com/drugs/DB15689InvestigationalAzoximer bromide is under investigation in clinical trial NCT04381377 (Efficacy and Safety of Polyoxidonium® in Hospitalized Patients With Coronavirus Disease COVID-19).
Categories: Heterocyclic Compounds, 1-RingSynonyms: Poly((1-(carboxymethyl)piperazin-1-ium-1,4-diyl bromide)ethylene-co-((piperazin-1,4-diyl 1-oxide)ethylene)Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15731InvestigationalORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord. … Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified on MSCs with enhanced clonogenicity and immunomodulatory properties.
Synonyms: ORBCEL Câ„¢, Orbcel-CFT516
go.drugbank.com/drugs/DB15732InvestigationalThis compound expresses a high-affinity 158V, CD16 (hnCD16) Fc receptor that has an enhanced binding ability to tumor-targeting antibodies, and is resistant to downregulation. … FT516 is currently being tested against acute myeloid leukemia, B-cell lymphoma, and solid tumors in combination with other compounds. It is also a potential therapy for COVID-19.
Virus Specific T-Cell
go.drugbank.com/drugs/DB15735InvestigationalThese T-cells are then isolated from the donor and expanded in a culture to generate more VSTs. … Virus Specific T-Cells (VSTs) are a target therapy that are generated for specific viral antigens. These products are generated from virus-naive or virus-experienced autologous or allogenic sources.
Synonyms: Viral Specific T-lymphocytes, HLA-matched Virus Specific T CellsCYP-001
go.drugbank.com/drugs/DB15739InvestigationalWhen activated with fibroblast growth factor-2 (FGF-2), MCAs create colonies with specific phenotypes. These cells are then able to differentiate into bone, cartilage, and adipose tissue. … These cells have advantage over other MSCs because a large amount can be obtained from a single healthy blood donor, negating the risks from donor-and expansion dependent variability.
Allogenic Pooled Olfactory Mucosa-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15740InvestigationalCurrently, OM-MSCs does not have wide application as there is not yet a standard and unambiguous protocol for OM-MSC collection, isolation, and therapeutic application.
Recombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741InvestigationalB38-CAP is structured as a carboxypeptidase and derived from _Paenibacillus sp._ The molecule, an Angiotensin Converting Enzyme 2 (ACE2)-like enzyme, shares structural similarities to the mammalian ACE2
Stem-cell derived exosome vesicle products
go.drugbank.com/drugs/DB15743ExperimentalThese exosomes can also consist of VEGF and matrix metalloproteinase-9 (MMP-9) which aid in angiogenesis and tissue repair. … While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins.
Recombinant human plasma gelsolin
go.drugbank.com/drugs/DB15746InvestigationalPlasma gelsolin (pGSN) is a protein found in the blood of healthy individuals which scavenges compounds left over from damaged tissues.