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Displaying results 861 - 870 of 10000 in total
  1. Drug

    Baloxavir marboxil

    go.drugbank.com/drugs/DB13997
    ApprovedInvestigational

    [A39895, A251755] It is a prodrug of [baloxavir] [L42855] with an improved absorption profile than its active metabolite due to the addition of a phenolic hydroxyl group to its structure. … [A251760] Baloxavir marboxil was first globally approved in Japan in February 2018,[A39895] followed by the US approval in October, 2018.

    Products: XOFLUZA FILM COATED TABLETS 20MG, XOFLUZA FILM COATED TABLETS 40MG
  2. Drug

    Delorazepam

    go.drugbank.com/drugs/DB01511
    IllicitInvestigational

    In addition to be long acting, delorazepam is relatively potent, with 1 mg of delorazepam being the equivalent of 10 mg diazepam. It has been approved for marketing in Italy. … Delorazepam is an active metabolite of the benzodiazepine known as cloxazolam. It is a long acting benzodiazepine which makes it superior in this sense to lorazepam which is short acting.

    International brands: EN, Delorazepam EGProducts: EN, DELORAZEPAM EG
  3. Drug

    Tetryzoline

    go.drugbank.com/drugs/DB06764
    Approved

    [L32584, L32589, L32594] It is also used in combination with other drug classes, such as antihistamines, corticosteroids, and glucocorticoids in other countries. … Tetryzoline is found in a wide array of over-the-counter eye drops, including the most common brand, Visine.

    Mixtures: OCTILIA ALLERGIA E INFIAMMAZIONE, OCTILIA ALLERGIA E INFIAMMAZIONECategories: Compounds used in a research, industrial, or household setting
  4. Drug

    Methoxsalen

    go.drugbank.com/drugs/DB00553
    ApprovedInvestigational

    It is a photoactive substance that forms DNA adducts in the presence of ultraviolet A irradiation. … A naturally occurring furocoumarin compound found in several species of plants, including Psoralea corylifolia.

    Categories: Compounds used in a research, industrial, or household settingProducts: MOPSALEM TABLETAS RECUBIERTAS, GIRAPROX® 500 MG TABLETAS RECUBIERTAS
  5. Drug

    Nortriptyline

    go.drugbank.com/drugs/DB00540
    ApprovedInvestigational

    [L11878] It is used in the treatment of major depression and is also used off-label for chronic pain and other conditions.[L11881]

    Categories: Dopamine D2 Receptor AntagonistsSynonyms: 10,11-dihydro-N-methyl-5H-dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N-methyl-1-propanamine
  6. Drug

    Phenylbutazone

    go.drugbank.com/drugs/DB00812
    ApprovedVet approvedWithdrawn

    Although phenylbutazone is effective in gouty arthritis, risk/benefit considerations indicate that this drug should not be employed for this disease. (From AMA Drug Evaluations Annual, 1994, p1822) … It is especially effective in the treatment of ankylosing spondylitis. It also is useful in rheumatoid arthritis and Reiter's syndrome (investigational indication).

    Synonyms: 3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine, 4-n-Butyl-1,2-diphenyl-3,5-pyrazolidinedioneProducts: FENILBUTAZONA 200 MG TABLETAS
  7. Drug

    Doconexent

    go.drugbank.com/drugs/DB03756
    ApprovedInvestigational

    It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. … It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function.

    Synonyms: 22:6(n-3)Mixtures: VINATAL DHA CAPSULA DE GELATINA BLANDA, Live-well™ Toco-E Capsule
  8. Drug

    Flavoxate

    go.drugbank.com/drugs/DB01148
    Approved

    It may have local anesthetic activity and direct relaxing effects on smooth muscle as well as some activity as a muscarinic antagonist. [PubChem] … A drug that has been used in various urinary syndromes and as an antispasmodic. Its therapeutic usefulness and its mechanism of action are not clear.

    Products: FLAVOXATO CLORHIDRATO 200 MG TABLETAS RECUBIERTAS, URISPAS 200 TABLET
  9. Drug

    Upadacitinib

    go.drugbank.com/drugs/DB15091
    ApprovedInvestigational

    [A189168] To reduce dose-related toxicity (as seen with some pan-JAK inhibitors) without significantly affecting efficacy, more selective JAK1 inhibitors, upadacitinib and [filgotinib], were developed. … [A189165] Despite a variety of therapeutic agents available for treatment, up to 40% of the patients do not respond to current therapies, including biological therapies.

    Products: RINVOQ 30 mg extended-release film coated tablets, RINVOQ 15mg Extended Release Film Coated Tablets
  10. Drug

    Procaterol

    go.drugbank.com/drugs/DB01366
    ApprovedWithdrawn

    It is a potent bronchodilator that may be administered orally or by aerosol inhalation.

    Products: MEPTIN TABLETS, MEPTIN MINI TABLETS