Search
Metabolism and Physiological Effects of Citrulline
smpdb.ca/view/SMP0126861MetabolicIn addition, citrulline and L-aspartic acid can be converted into argininosuccinic acid through the action of the enzyme argininosuccinate synthase. … In particular, citrulline can be biosynthesized from carbamoyl phosphate and ornithine which is catalyzed by the enzyme ornithine carbamoyltransferase.
Ferrous ascorbate
go.drugbank.com/drugs/DB14490ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household setting, Diet, Food, and NutritionProducts: Ascofer Cap 275mgLovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigationalwere found in clinical studies to result in a 45.8% to 54.6% decrease in LDL cholesterol levels, while lovastatin has been found to have an average decrease in LDL-C of 25-40%. … [A181084] Elevated cholesterol levels, and in particular, elevated low-density lipoprotein (LDL) levels, are an important risk factor for the development of CVD.
Categories: lovastatin and nicotinic acidProducts: LOVAHEXAL 10MG TABL, LOVABETA 10MG TABLETTENMetabolism and Physiological Effects of Putrescine
smpdb.ca/view/SMP0123276MetabolicWhile putrescine is important for interactions and processes involving, DNA, RNA and proteins, at high levels it is also a protein bound uremic toxin found in the body that can inhibit erythropoietin production … Like other polyamines such as spermidine and spermine, putrescine can also be obtained directly from diet as well.
Metabolism and Physiological Effects of Xanthosine
smpdb.ca/view/SMP0124866MetabolicPurines can be made endogenously in the body or can be obtained exogenously from foods such as red meat. The purines are guanine and adenine. These undergo metabolism in the liver to form xanthosine. … Xanthosine then enters the blood where it can have detrimental effects on other organs such as the kidney, causing renal failure and the heart causing cardiovascular disease.
Metabolism and Physiological Effects of Uridine
smpdb.ca/view/SMP0124871MetabolicL-glutamine is obtained form protein sources in the diet and is metabolized to uridine in the liver. … Finally, uridine 5'-monophosphate forms uridine via cytosolic 5'-nucleotidase 1B. uridine enters the blood stream and may have affect tissues such as the kidney, where it can contribute to renal failure
Enzymes: CAD proteinVonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigational[A253707] In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and as an adjunct to _Helicobacter pylori_ (_H. pylori_) eradication. … Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations.
Categories: Alimentary Tract and Metabolism, vonoprazan and amoxicillinSynonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamineAmbrosia confertiflora pollen
go.drugbank.com/drugs/DB10872ApprovedAmbrosia confertiflora pollen is the pollen of the Ambrosia confertiflora plant. Ambrosia confertiflora pollen is mainly used in allergenic testing.
Synonyms: weakleaf bur ragweed pollen extractFosinopril
go.drugbank.com/drugs/DB00492ApprovedInvestigationalFosinopril may be used to treat mild to moderate hypertension, as an adjunct in the treatment of congestive heart failure, and to slow the rate of progression of renal disease in hypertensive individuals … ATII regulates blood pressure and is a key component of the renin-angiotensin-aldosterone system (RAAS).
Mixtures: Fosinopril Sodium and Hydrochlorothiazide, Fosinopril Sodium and HydrochlorothiazideCategories: ACE Inhibitors and Diuretics, fosinopril and diureticsEbastine
go.drugbank.com/drugs/DB11742ApprovedInvestigationalWithdrawnEbastine is under investigation for the treatment of Irritable Bowel Syndrome (IBS). Ebastine has been investigated for the treatment of Urticaria.
Products: EBASTEL 10MG, EBASTIN ARISTO 10MG