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Displaying results 871 - 880 of 10000 in total
  1. Indication

    Anorexia

    go.drugbank.com/conditions/DBCOND0004522
    Drugs: Dronabinol · Hemicellulase · Itopride · Megestrol acetate
    Synonyms: No appetite
  2. Target

    Insulin-like growth factor 1 receptor

    go.drugbank.com/bio_entities/BE0000858
    TargetHumans

    JNK kinases can also be activated by the IGF1R. … Phosphorylation of JAK proteins can lead to phosphorylation/activation of signal transducers and activators of transcription (STAT) proteins.

    Synonyms: IGF-I receptor, Insulin-like growth factor I receptor
  3. Target

    DNA-binding transcriptional regulator NtrC

    go.drugbank.com/bio_entities/BE0001282
    TargetSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

    Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open p...

    Synonyms: Nitrogen regulator I, Nitrogen regulation protein NR(I)
  4. Target

    Apolipoprotein L1

    go.drugbank.com/bio_entities/BE0009069
    TargetHumans

    May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver. A component of trypanosome lytic factor of human serum; plays a crucial role in kil...

    Synonyms: ApoL-I, Apolipoprotein L-I
  5. Target

    Geranylgeranyl transferase type-1 subunit beta

    go.drugbank.com/bio_entities/BE0001142
    TargetHumans

    Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Known substrates include...

    Synonyms: GGTase-I-beta, Geranylgeranyl transferase type I subunit beta
  6. Target

    Cysteine dioxygenase type 1

    go.drugbank.com/bio_entities/BE0000569
    TargetEnzymeHumans

    Rate-limiting enzyme of the cysteine catabolic process to taurine, which catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen

    Synonyms: CDO-I, Cysteine dioxygenase type I
  7. Drug

    Meticillin

    go.drugbank.com/drugs/DB01603
    ApprovedInvestigational

    One of the penicillins which is resistant to penicillinase but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: (2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2,6-Dimethoxybenzamido)penicillanic acid
  8. Drug

    Inositol

    go.drugbank.com/drugs/DB13178
    ApprovedInvestigationalWithdrawn

    [L2560] Inositol can be found as an ingredient of OTC products by Health Canada but all current product whose main ingredient is inositol are discontinued. … Inositol is a collection of nine different stereoisomers but the name is usually used to describe only the most common type of inositol, myo-inositol.

    Mixtures: Super Daily No 2, Vitamin B + C CapCategories: Vitamin B Complex
  9. Drug

    Magnesium hydroxide

    go.drugbank.com/drugs/DB09104
    ApprovedInvestigational

    Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. … It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).

    Mixtures: Neo Tigol Tab, DYNA-U TABLETProducts: Milk Of Magnesia 7% To 8.5%, Dermagran II Ointment 0.25%
  10. Drug

    Dipropylene glycol

    go.drugbank.com/drugs/DB14140
    Investigational

    Synonyms: 4-Oxa-2,6-heptandiol, 1,1'-Oxybis(2-propanol)Products: Abelia pomegranate bounce up mask, Dr.g A-clear Balancing Moisturizer