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Displaying results 871 - 880 of 10000 in total
  1. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    [A181673] It gained FDA approval in 1987 and although it was initially intended for the treatment of depression, today it is commonly prescribed to manage depression in addition to various other pathologies … Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).

    Synonyms: (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine, (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamineInternational brands: Animex-On
  2. Drug

    Diltiazem

    go.drugbank.com/drugs/DB00343
    ApprovedInvestigational

    Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. … , and rest-related cramps in the lower extremities.

    Categories: Agents for Treatment of Hemorrhoids and Anal Fissures for Topical Use, P-glycoprotein inhibitorsSynonyms: d-cis-diltiazem, (+)-cis-5-[2-(dimethylamino)ethyl]-2,3-dihydro-3-hydroxy-2-(p-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one acetate ester
  3. Drug

    Candesartan cilexetil

    go.drugbank.com/drugs/DB00796
    ApprovedInvestigational

    the blood pressure increasing effects of angiotensin II. … Candesartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents

    Mixtures: CANDAM ® H 5/32/12.5, CANDAM® H 5/16/12.5 MGCategories: Angiotensin II receptor antagonists, Angiotensin II Antagonists and Diuretics
  4. Drug

    Verapamil

    go.drugbank.com/drugs/DB00661
    ApprovedInvestigational

    into therapy in the early 1960s. … Verapamil is a phenylalkylamine calcium channel blocker used in the treatment of high blood pressure, heart arrhythmias, and angina,[L8791] and was the first calcium channel antagonist to be introduced

    Mixtures: TARKA® SR240/4 TABLETAS., TARKA® SR TABLETASCategories: MATE 1 Inhibitors, MATE 2 Inhibitors
  5. Drug

    Exenatide

    go.drugbank.com/drugs/DB01276
    ApprovedInvestigational

    [L42685,L42690] Bydureon, the brand name product of extended-release exenatide in an injectable suspension, was discontinued in 2021. … Exenatide is a glucagon-like peptide-1 (GLP-1) analog[L42690].

    Synonyms: Exendin 4, Exendin-4Categories: Drugs Used in Diabetes, Glucagon-like peptide-1 (GLP-1) analogues
  6. Drug

    Plasma protein fraction (human)

    go.drugbank.com/drugs/DB13968
    ApprovedInvestigational

    [L2262] The proteins in PPFh are stabilized with sodium caprylate and acetyltryptophan and it contains some electrolytes such as sodium, potassium and chloride.[L2261] … It is also stated that no more than 1% of the total protein should be gamma globulin.[L2260] PPFh is a sterile, frozen solution of solvent/detergent treated human plasma.

    Products: OCTAPLAS Blood Group O, SANDOGLOBULINA 6 G
  7. Drug

    Gliclazide

    go.drugbank.com/drugs/DB01120
    ApprovedInvestigational

    Medications in this class differ in their dose, rate of absorption, duration of action, route of elimination and binding site on their target pancreatic β cell receptor. … The risk of hypoglycemia is increased in elderly, debilitated and malnourished individuals.

    Synonyms: 1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea, 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)ureaCategories: Drugs Used in Diabetes, combinations of sulfonamides
  8. Drug

    Norepinephrine

    go.drugbank.com/drugs/DB00368
    ApprovedInvestigational

    It is also found in plants and is used pharmacologically as a sympathomimetic. … Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus.

    Synonyms: (R)-4-(2-amino-1-hydroxyethyl)-1,2-benzenediol, 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediolMixtures: XYLONOR %3 NORADRENALINE ENJEKSIYONLUK SOLUSYON ICEREN KULLANIMA HAZIR 50 KARTUS
  9. Drug

    Ivabradine

    go.drugbank.com/drugs/DB09083
    ApprovedInvestigational

    Ivabradine, brand name Corlanor, was approved by the FDA in April 2015 for the treatment of chronic heart failure in patients with an ejection fraction of ≤35%, in sinus rhythm with resting heart rate … Ivabradine acts by selectively inhibiting the "funny" channel pacemaker current (If) in the sinoatrial node in a dose-dependent fashion, resulting in a lower heart rate and thus more blood to flow to the

    Mixtures: CARIVALAN 25/5, CARIVALAN 6.25/5Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring
  10. Drug

    Famotidine

    go.drugbank.com/drugs/DB00927
    ApprovedInvestigational

    It is commonly used in gastrointestinal conditions related to acid secretion, such as gastric ulcers and gastroesophageal reflux disease (GERD), in adults and children. … [L11166] While oral formulations of famotidine are more commonly used, the intravenous solution of the drug is available for use in hospital settings.[L11142]

    Synonyms: N-Sulfamoyl-3-((2-guanidinothiazol-4-yl)methylthio)propionamide, 3-(((2-((Diaminomethylene)amino)-4-thiazolyl)methyl)thio)-N(sup 2)-sulfamoylpropionamidineInternational brands: Sedanium-R