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NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial
go.drugbank.com/bio_entities/BE0000493TargetHumansPlays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903 … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor
Synonyms: Complex I-75kDTranslocation protein SEC62
go.drugbank.com/bio_entities/BE0009211TargetPlasmodium falciparum (isolate 3D7)Synonyms: Secretory complex protein 62Monopotassium phosphate
go.drugbank.com/drugs/DB09413ApprovedInvestigationalVet approvedIt can be used in fertilizer mixtures to reduce escape of ammonia by keeping pH low.
Mixtures: Clinimix 3 % G-E - Infusionsbeutel, Clinimix 5 % G-E - InfusionsbeutelCategories: Compounds used in a research, industrial, or household settingHypromellose
go.drugbank.com/drugs/DB11075ApprovedInvestigationalIt acts as a thickening agent, coating polymer, bioadhesive, solubility enhancer in solid dispersions, and binder in the process of granulation and in modified release formulations [A24840]. … Hypromellose is also found in eye drops as a lubricant [L1803].
Mixtures: Rohto All-In-One, Core Values Eye Drops Dry Eye ReliefCategories: Compounds used in a research, industrial, or household settingPhenylpropanolamine
go.drugbank.com/drugs/DB00397ApprovedVet approvedWithdrawnCurrently, it is withdrawn from the market in Canada and the United States due to the risk for hemorrahgic strokes.
Mixtures: COUGH - EN, COUGH - EN PLUSLevodopa
go.drugbank.com/drugs/DB01235ApprovedInvestigationalThe first developed drug product that was approved by the FDA was a levodopa and carbidopa combined product called Sinemet that was approved on May 2, 1975[A177781,L6133]. … Levodopa can be metabolised to dopamine on either side of the blood-brain barrier and so it is generally administered with a dopa decarboxylase inhibitor like carbidopa to prevent metabolism until after
Mixtures: LEV/CAR/EN AL100/25/200, LEV/CAR/EN AL200/50/200Calcium lactate
go.drugbank.com/drugs/DB13231ApprovedVet approvedCalcium lactate is also found in daily dietary supplements as a source of calcium. It is also available in various hydrate forms, where calcium lactate pentahydrate is the most common.
Mixtures: Pro Enz Tab, Calcium Lactate Et Magnesium SulfateMilrinone
go.drugbank.com/drugs/DB00235ApprovedInvestigationalmetabolites, resulting in complex systemic pathologies. … [A228333] As a PDE-III inhibitor, milrinone results in increased cAMP levels and improves cardiac function and peripheral vasodilation in acute decongested heart failure.
Mixtures: Milrinone Lactate in DextroseCategories: Compounds used in a research, industrial, or household settingChromium
go.drugbank.com/drugs/DB11136ApprovedInvestigationalin commercial settings and are known to be human carcinogens [L1982]. … Trivalent chromium (Cr(III)) ion is considered to be an essential dietary trace element as it is involved in metabolism of blood glucose, regulation of insulin resistance and metabolism of lipids.
Mixtures: ADDAMEL N, Calcium With Mg Zn Mn Cu CR Si and Vit. C & DMagnesium carbonate
go.drugbank.com/drugs/DB09481ApprovedMagnesium carbonate, also known as magnesite, is a common over the counter remedy for heartburn and upset stomach caused by overproduction of acid in the stomach [FDA Label].
Mixtures: Sintra-ES, Calcium Et Magnesium TabCategories: Compounds used in a research, industrial, or household setting