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Displaying results 8801 - 8810 of 10000 in total

Drug
Diosmetin
go.drugbank.com/drugs/DB11259
Approved
Pharmacologically, diosmetin is reported to exhibit anticancer, antimicrobial, antioxidant, oestrogenic and anti-inflamatory activities [A27231]. It also acts as a weak TrkB receptor agonist [A27230]. … Diosmetin is an O-methylated flavone and the aglycone part of the flavonoid glycosides diosmin that occurs naturally in citrus fruits [A27231].
Synonyms: 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone, 3',5,7-trihydroxy-4'-methoxyflavoneCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
Drug
Dihydroergocornine
go.drugbank.com/drugs/DB11273
Approved
[A32965] Dihydroergocornine presents a formula of 9,10 alpha-dihydro-12'-hydroxy-2',5'alpha-bis(1-methylethyl)-ergotaman-3',6',18-trione. … [T190] It is found as one of the components in the ergoloid mesylate mixture. To know more about this mixture please refer to [DB01049]
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Dipyrithione
go.drugbank.com/drugs/DB11327
Approved
[L2611] It is currently used as a pesticide, and not used in any FDA approved drug products. … Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available.
Categories: Heterocyclic Compounds, 1-Ring
Drug
Guaiacol
go.drugbank.com/drugs/DB11359
Approved
Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin. … Guaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma.
Synonyms: 1-hydroxy-2-methoxybenzene, 2-methoxyl-4-vinylphenolMixtures: NOKTOS ® ADULTOS JARABE.
Drug
Danofloxacin
go.drugbank.com/drugs/DB11393
ExperimentalVet approved
Danofloxacin is an antibiotic agent from the family of the fluoroquinolones used in veterinary medicine.
Categories: 4-Quinolones, Heterocyclic Compounds, 2-Ring
Drug
Medetomidine
go.drugbank.com/drugs/DB11428
ExperimentalVet approved
Medetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. … The marketed product is a racemic mixture of two stereoisomers from which dexmedetomidine is the main active isomer.
Synonyms: (±)-4-(α,2,3-trimethylbenzyl)imidazoleCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor Agonists
Drug
Oleandomycin
go.drugbank.com/drugs/DB11442
ExperimentalVet approved
Oleandomycin is a macrolide antibiotic, though it is less effective than erythromycin. It is synthesized from strains of _Streptomyces antibioticus_.
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
Drug
Ceftiofur
go.drugbank.com/drugs/DB11485
ExperimentalVet approved
It is marketed by pharmaceutical company Zoetis as Excenel, and is the active ingredient in that company's Specramast LC (lactating cow formula) product. … Ceftiofur is a third generation cephalosporin antibiotic, first described in 1987, and now used in veterinary medicine.
Categories: Heterocyclic Compounds, 2-Ring
Drug
Nalorphine
go.drugbank.com/drugs/DB11490
ExperimentalVet approved
Nalorphine is a mixed opioid agonist–antagonist. … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Categories: Heterocyclic Compounds with 4 or More Rings
Drug
Sarafloxacin
go.drugbank.com/drugs/DB11491
ApprovedVet approvedWithdrawn
Sarafloxacin is a quinolone antibiotic drug, which was discontinued by its manufacturer, Abbott Laboratories, before receiving approval for use in the US or Canada.
Categories: 4-Quinolones, Cytochrome P-450 CYP1A2 Inhibitors