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Asenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalIt is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009. … Developed by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with
Categories: Diazepines, Oxazepines, Thiazepines and OxepinesProducts: SAPHRIS SUBLINGUAL TABLET 10MG, SYCREST 10MG DILALTI TABLET, 100 TABLETNateglinide
go.drugbank.com/drugs/DB00731ApprovedThe average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those naïve to oral antidiabetic agents. … Nateglinide is an amino acid derivative that induces an early insulin response to meals decreasing postprandial blood glucose levels.
Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismProducts: Starlix 60mg, Starlix 120mgPanobinostat
go.drugbank.com/drugs/DB06603ApprovedInvestigationalPanobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. … Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the most potent DAC inhibiting agent available on the market.
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide, 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)-Coal tar
go.drugbank.com/drugs/DB11082ApprovedIt has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema. … Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas.
Mixtures: Pete and Pedro, Multi-action Denorex 2-IN-1 Dandruff Shampoo + ConditionerProducts: Skin and scalp, Skin and Scalp BodyVonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigational[A253707] In February 2015, vonoprazan was first marketed in Japan for the treatment of acid-related disorders and as an adjunct to _Helicobacter pylori_ (_H. pylori_) eradication. … Unlike proton-pump inhibitors, PCABs are not affected by CYP2C19 genetic polymorphisms and do not require acid-resistant formulations.
Synonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamineCategories: Alimentary Tract and Metabolism, vonoprazan and amoxicillinRomosozumab
go.drugbank.com/drugs/DB11866ApprovedInvestigationalRomosozumab prevents bone resorption and induces the formation of bone though it is associated with an increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. … Romosozumab also demonstrates a faster and larger increase in bone density than teriparatide[A177050]. Romosozumab is marketed in the United States by Amgen under the brand name Evinity[L5921].
Categories: Amino Acids, Peptides, and Proteins, Drugs Affecting Bone Structure and MineralizationProducts: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 MLPasireotide
go.drugbank.com/drugs/DB06663ApprovedInvestigationalPasireotide is a synthetic long-acting cyclic hexapeptide with somatostatin-like activity. It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.
Categories: Pituitary and Hypothalamic Hormones and Analogues, Sex Hormones and InsulinsProducts: SIGNIFOR LAR POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION 20MG, Signifor LAR 20mg powder and solvent for suspension for injectionCoenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Mixtures: IFEX and MESNEX, IFEX and MESNEXCategories: Cough and Cold Preparations, Compounds used in a research, industrial, or household settingVinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalIn murine tumors and human tumor xenografts, vinflunine exhibits an antitumor efficacy than [DB00361], [DB00570], and [DB00541] [A31975]. … In 2009, vinflunine was approved by the European Medicines Agency (EMA) as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment [A32626].
Categories: Antineoplastic and Immunomodulating AgentsProducts: JAVLOR 250MG/10ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, JAVLOR 50MG/2ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADETMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Categories: Antiparasitic Products, Insecticides and RepellentsProducts: QUEMOX TABLET 500MG, QUEMOX GRANULES 500MG