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Saxagliptin
go.drugbank.com/drugs/DB06335ApprovedInvestigationalSaxagliptin (rINN) is an orally active hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. FDA approved on July 31, 2009.
Mixtures: KOMBIGLYZE XR TABLET 5MG/500MG, KOMBIGLYZE XR TABLET 5MG/1000MGCategories: Drugs Used in Diabetes, DPP-IV InhibitorsRomosozumab
go.drugbank.com/drugs/DB11866ApprovedInvestigationalRomosozumab prevents bone resorption and induces the formation of bone though it is associated with an increased risk of cardiac death, heart attack, and stroke in one study[L5921,L5924]. … Romosozumab also demonstrates a faster and larger increase in bone density than teriparatide[A177050]. Romosozumab is marketed in the United States by Amgen under the brand name Evinity[L5921].
Categories: Amino Acids, Peptides, and Proteins, Drugs Affecting Bone Structure and MineralizationProducts: EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105MG/1.17ML, EVENITY SOLUTION FOR INJECTION IN PRE-FILLED SYRINGE 105 MG/1.17 MLVinflunine
go.drugbank.com/drugs/DB11641ApprovedInvestigationalIn murine tumors and human tumor xenografts, vinflunine exhibits an antitumor efficacy than [DB00361], [DB00570], and [DB00541] [A31975]. … In 2009, vinflunine was approved by the European Medicines Agency (EMA) as a second-line therapy of metastatic and advanced urothelial cancer after failure of platinum-based treatment [A32626].
Categories: Antineoplastic and Immunomodulating AgentsProducts: JAVLOR 250MG/10ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADET, JAVLOR 50MG/2ML İNFÜZYONLUK KONSANTRE ÇÖZELTİ, 1 ADETNilotinib
go.drugbank.com/drugs/DB04868ApprovedInvestigationalA Phase I clinical trial in 2006 showed that this drug was relatively safe and offered significant therapeutic benefits in cases of CML which were found to be resistant to treatment with imatinib (Gleevec … Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML).
Categories: Antineoplastic and Immunomodulating AgentsProducts: TASIGNA CAPSULE 50MG, Tasigna 50mg CapsulesLormetazepam
go.drugbank.com/drugs/DB13872ApprovedLormatazepam is an orally available benzodiazepine used in the UK for the treatment of short-term insomnia [L927]. … It is marketed by Auden Mckenzie (Pharma Division) in 0.5 and 1 mg tablet formulations.
Categories: Hypnotics and Sedatives, Benzodiazepines and benzodiazepine derivativesSynonyms: N-MethyllorazepamCoal tar
go.drugbank.com/drugs/DB11082ApprovedIt has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema. … Coal tar is a brown or black liquid of extremely high viscosity. Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas.
Mixtures: Pete and Pedro, Multi-action Denorex 2-IN-1 Dandruff Shampoo + ConditionerProducts: Skin and scalp, Skin and Scalp BodyFlavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigational[L54226] In addition to its systemic use as a means of riboflavin supplementation, a topical ophthalmic preparation of FMN was approved by the FDA in October 2025 for use as a photoenhancer in epithelium-on … [A274616,L54226] FMN is composed of an isoalloxazine ring - which serves as the active redox center - attached to a ribityl phosphate chain.
Mixtures: Tini-cal Ampoules, B Complex W C and B12 InjCategories: Enzymes and Coenzymes, Nucleic Acids, Nucleotides, and NucleosidesPanobinostat
go.drugbank.com/drugs/DB06603ApprovedInvestigationalPanobinostat is an oral deacetylace (DAC) inhibitor approved on February 23, 2015 by the FDA for the treatment of multiple myeloma. … Panobinostat acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor) and it is the most potent DAC inhibiting agent available on the market.
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: (2E)-N-hydroxy-3-[4-({[2-(2-methyl-1H-indol-3-yl)ethyl]amino}methyl)phenyl]acrylamide, 2-PROPENAMIDE, N-HYDROXY-3-(4-(((2-(2-METHYL-1H-INDOL-3-YL)ETHYL)AMINO)METHYL)PHENYL)-, (2E)-Capsicum oleoresin
go.drugbank.com/drugs/DB11131ApprovedCapsicum oleoresin is contained in pepper sprays when suspended in water, and acts an active lachrymatory agent that induces irritation, lacrimation, pain, and temporary blindness when in contact with … Capsicum oleoresin is an oily organic resin derived from the fruit of plants in the Capsicum genus, such as chilli peppers.
Mixtures: Half and Half Balm, Hot Spice and IceProducts: Sheffield Arthritis and Muscle Pain Relief, Diabet AidCoenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Mixtures: IFEX and MESNEX, IFEX and MESNEXCategories: Cough and Cold Preparations, Compounds used in a research, industrial, or household setting