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Displaying results 881 - 890 of 2232 in total
  1. Drug

    Quinagolide

    go.drugbank.com/drugs/DB09097
    ApprovedWithdrawn

    Quinagolide is a non-ergot-derived selective dopamine D2 receptor agonist used for the treatment of elevated levels of prolactin or hyperprolactinaemia. Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility a...

    Categories: Genito Urinary System and Sex Hormones
  2. Drug

    NSI-566

    go.drugbank.com/drugs/DB17954
    Investigational

    NSI-566 is a stem cell therapy consisting of human spinal cord-derived neural stem cells.

  3. Drug

    Stem-cell derived exosome vesicle products

    go.drugbank.com/drugs/DB15743
    Experimental

    While many contain a conserved set of proteins, they also carry unique tissue type-specific proteins. … Mesenchymal stem cells (MSCs) exert their therapeutic effects through multiple modalities, including paracrine factors such as exosomes.

    Synonyms: Stem-cell derived exosome vesicles, Stem-cell derived extracellular vesicles
  4. Drug

    OSSM-007

    go.drugbank.com/drugs/DB18553
    Experimental

    OSSM-007 consists of interferon-gamma primed allogeneic mesenchymal stem cells.

  5. Drug

    Dilanubicel

    go.drugbank.com/drugs/DB18722
    Investigational

    Dilanubicel consists of ex vivo expanded hematopoietic stem and progenitor cells.

  6. Drug

    Etonogestrel

    go.drugbank.com/drugs/DB00294
    ApprovedInvestigational

    Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and F...

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  7. Drug

    Ulipristal

    go.drugbank.com/drugs/DB08867
    ApprovedInvestigational

    It also binds to glucocorticoid receptor, however compared to mifepristone (a progesterone receptor antagonist), ulipristal is more tolerable and has lower glucocorticoid activity and better binding affinity … Ulipristal is currently recommended as first line therapy for emergency contraception, due to improved efficacy and similar side effect profile as compared to the traditional use of levonorgestrel or the

    Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital System
  8. Target

    ATPase GET3

    go.drugbank.com/bio_entities/BE0000750
    TargetHumans

    This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1/WRB and CAMLG/GET2, where the tail-anchored protein is released for insertion.

    Synonyms: Transmembrane domain recognition complex 40 kDa ATPase subunit
  9. Target

    Histone-lysine N-methyltransferase SETD7

    go.drugbank.com/bio_entities/BE0002524
    TargetHumans

    Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3 (PubMed:11779497, PubMed:11850410, PubMed:12540855, PubMed:12588998, PubMed:16141209). H3 'Lys-4' methylation represents a specific tag for epigenetic trans...

    Synonyms: SET domain-containing protein 7
  10. Drug

    Thiamine

    go.drugbank.com/drugs/DB00152
    ApprovedInvestigationalNutraceuticalVet approved

    Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki ...

    Mixtures: Se-Natal, Se-Natal 19Categories: Vitamin B Complex