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Probucol
go.drugbank.com/drugs/DB01599ApprovedInvestigationalWithdrawnA drug used to lower LDL and HDL cholesterol yet has little effect on serum-triglyceride or VLDL cholesterol. (From Martindale, The Extra Pharmacopoeia, 30th ed, p993).
Categories: Compounds used in a research, industrial, or household settingSynonyms: Acetone bis(3,5-di-tert-butyl-4-hydroxyphenyl) mercaptoleLopinavir
go.drugbank.com/drugs/DB01601ApprovedInvestigational[saquinavir], [nelfinavir]), lopinavir is a peptidomimetic molecule - it contains a hydroxyethylene scaffold that mimics the peptide linkage typically targeted by the HIV-1 protease enzyme but which itself … cannot be cleaved, thus preventing the activity of the HIV-1 protease.
Mixtures: LOPIMUNE®, LOPIMUNE®Categories: P-glycoprotein inducers, P-glycoprotein inhibitorsBacampicillin
go.drugbank.com/drugs/DB01602ApprovedWithdrawnBacampicillin is a prodrug of ampicillin and is microbiologically inactive. It is absorbed following oral administration. … It is microbiologically active as ampicillin, and exerts a bactericidal action through the inhibition of the biosynthesis of cell wall mucopeptides.
Categories: Penicillin G, Heterocyclic Compounds, 2-RingSynonyms: 1-[(ethoxycarbonyl)oxy]ethyl (2S,5R,6R)-6-{[(2R)-2-amino-2-phenylacetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 1'-ethoxycarbonyloxyethyl-(6-D-α-aminophenylacetamido)penicillanatePivampicillin
go.drugbank.com/drugs/DB01604ApprovedWithdrawnPivalate ester analog of ampicillin.
Categories: Penicillin G, Heterocyclic Compounds, 2-RingPericiazine
go.drugbank.com/drugs/DB01608ApprovedPericiazine is a phenothiazine of the piperidine group. … Pericyazine, like other phenothiazines, is presumed to act principally in the subcortical areas, by producing what has been described as a central adrenergic blockade.
Categories: Heterocyclic Compounds, 3-Ring, Adrenergic alpha-1 Receptor AntagonistsSynonyms: 2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine, Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazineDeferasirox
go.drugbank.com/drugs/DB01609ApprovedInvestigationalDeferasirox is an iron chelator and the first oral medication FDA approved for chronic iron overload in patients receiving long term blood transfusions.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP1A2 InhibitorsProducts: RASIROX® 250MG, RASIROX® 500 MGHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer.[A183047] Hydroxychloroquine is an aminoquinoline like [chloroquine]. … [L8072] A recent study reported a fatality in the group being treated with hydroxychloroquine for COVID-19.[A192546]
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: 2-(N-(4-(7-chlor-4-chinolylamino)-4-methylbutyl)ethylamino)ethanol, 7-chloro-4-(4-(N-ethyl-N-β-hydroxyethylamino)-1-methylbutylamino)quinolineAmyl Nitrite
go.drugbank.com/drugs/DB01612ApprovedIts use as a prescription medicine comes from its ability to lower blood pressure. As an inhalant, it also has psychoactive effect which has led to illegal drug use.
Synonyms: 1-nitropentane, n-Amyl nitriteAcepromazine
go.drugbank.com/drugs/DB01614InvestigationalVet approvedAcepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.
Categories: Heterocyclic Compounds, 3-Ring, Adrenergic alpha-1 Receptor AntagonistsSynonyms: 1-[10-(3-dimethylamino-propyl)-10H-phenothiazin-2-yl]-ethanone, 10-(3-dimethylaminopropyl)phenothiazine-3-ethyloneAlverine
go.drugbank.com/drugs/DB01616ApprovedInvestigationalWithdrawnAlverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It is therefore useful in treating irritable bowel syndrome (IBS) and similar conditions.
Mixtures: METEOSPASMYL® CAPSULAS BLANDAS, METEOSPASMYL® CAPSULAS BLANDASCategories: Serotonin 5-HT1 Receptor Antagonists, Serotonin 5-HT1A Receptor Antagonists