Search
Fatty acid-binding protein, intestinal
go.drugbank.com/bio_entities/BE0003591CarrierTargetHumansFABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. … Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids.
Polypeptides: Fatty acid-binding protein, intestinalSynonyms: Fatty acid-binding protein 2, Intestinal-type fatty acid-binding proteinIleal sodium/bile acid cotransporter
go.drugbank.com/bio_entities/BE0003643TransporterTargetHumansTransports various bile acids, unconjugated or conjugated, such as cholate and taurocholate (PubMed:7592981, PubMed:9458785, PubMed:9856990). … Also responsible for bile acid transport in the renal proximal tubules, a salvage mechanism that helps conserve bile acids (Probable).
Polypeptides: Ileal sodium/bile acid cotransporterSynonyms: Ileal Na(+)/bile acid cotransporter, Apical sodium-dependent bile acid transporterAlpha-1-acid glycoprotein 2
go.drugbank.com/bio_entities/BE0003663TargetHumansAlso binds synthetic drugs and influences their distribution and availability. Appears to function in modulating the activity of the immune system during the acute-phase reaction
Polypeptides: Alpha-1-acid glycoprotein 2Folic acid synthesis protein FOL1
go.drugbank.com/bio_entities/BE0004658TargetBaker's yeastCatalyzes three sequential steps of tetrahydrofolate biosynthesis.
Polypeptides: Folic acid synthesis protein FOL1Free fatty acid receptor 2
go.drugbank.com/bio_entities/BE0010131TargetHumansIn omnivorous mammals, the short chain fatty acids acetate, propionate and butyrate are produced primarily by the gut microbiome that metabolizes dietary fibers. … Among SCFAs, the fatty acids containing less than 6 carbons, the most potent activators are probably acetate, propionate and butyrate (PubMed:12496283, PubMed:12711604).
Polypeptides: Free fatty acid receptor 2Cellular retinoic acid-binding protein 1
go.drugbank.com/bio_entities/BE0000508CarrierTransporterTargetHumansCytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors
Polypeptides: Cellular retinoic acid-binding protein 1Synonyms: Cellular retinoic acid-binding protein IProton-coupled amino acid transporter 1
go.drugbank.com/bio_entities/BE0000536TargetTransporterHumansElectrogenic proton/amino acid symporter with selectivity for small apolar L-amino acids, their D-enantiomers and selected amino acid derivatives such as 4-aminobutanoate/GABA (PubMed:12527723, PubMed: … May be involved in the efflux from the lysosomal compartment of neutral amino acids resulting from proteolysis (By similarity).
Polypeptides: Proton-coupled amino acid transporter 1Synonyms: Proton/amino acid transporter 1Retinoic acid receptor responder protein 1
go.drugbank.com/bio_entities/BE0000653TargetHumansInhibitor of the cytoplasmic carboxypeptidase AGBL2, may regulate the alpha-tubulin tyrosination cycle
Polypeptides: Retinoic acid receptor responder protein 1Cellular retinoic acid-binding protein 2
go.drugbank.com/bio_entities/BE0000782CarrierTransporterHumansTransports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors
Polypeptides: Cellular retinoic acid-binding protein 2Synonyms: Cellular retinoic acid-binding protein IINicotinamide/nicotinic acid mononucleotide adenylyltransferase 3
go.drugbank.com/bio_entities/BE0001832TargetHumansCan also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. … Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP (PubMed:16118205, PubMed:17402747, PubMed:26616331).
Polypeptides: Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3