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Displaying results 81 - 90 of 561 in total
  1. Target

    Protein S100-A4

    go.drugbank.com/bio_entities/BE0004350
    TargetHumans

    Calcium-binding protein that plays a role in various cellular processes including motility, angiogenesis, cell differentiation, apoptosis, and autophagy (PubMed:16707441, PubMed:23752197, PubMed:30713770

    Synonyms: S100 calcium-binding protein A4, Placental calcium-binding protein
  2. Target

    Protein S100-A7

    go.drugbank.com/bio_entities/BE0003756
    TargetHumans

    Synonyms: S100 calcium-binding protein A7Function: calcium ion binding
  3. Target

    Transient receptor potential cation channel subfamily V member 5

    go.drugbank.com/bio_entities/BE0005112
    TransporterHumans

    The channel is activated by low internal calcium level and the current exhibits an inward rectification (PubMed:11549322, PubMed:18768590). … Constitutively active calcium selective cation channel thought to be involved in Ca(2+) reabsorption in kidney and intestine (PubMed:11549322, PubMed:18768590).

    Synonyms: Calcium transport protein 2, Epithelial calcium channel 1Function: calcium channel activity
  4. Target

    Protein S100-G

    go.drugbank.com/bio_entities/BE0004083
    TargetCarrierHumans

    Synonyms: S100 calcium-binding protein G, Vitamin D-dependent calcium-binding protein, intestinalFunction: calcium ion binding
  5. Target

    Protein S100-A2

    go.drugbank.com/bio_entities/BE0003602
    TargetHumans

    May function as calcium sensor and modulator, contributing to cellular calcium signaling.

    Synonyms: S100 calcium-binding protein A2Function: calcium ion binding
  6. Target

    Calbindin

    go.drugbank.com/bio_entities/BE0008690
    CarrierHumans

    Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase

    Synonyms: Vitamin D-dependent calcium-binding protein, avian-typeFunction: calcium ion binding
  7. Target

    Calpain-3

    go.drugbank.com/bio_entities/BE0003470
    TargetHumans

    Calcium-regulated non-lysosomal thiol-protease. Proteolytically cleaves CTBP1 at 'His-409'. Mediates, with UTP25, the proteasome-independent degradation of p53/TP53 (PubMed:23357851, PubMed:27657329)

    Synonyms: Calcium-activated neutral proteinase 3, Muscle-specific calcium-activated neutral protease 3Function: calcium ion binding
  8. Target

    Peripheral plasma membrane protein CASK

    go.drugbank.com/bio_entities/BE0002641
    TargetHumans

    Multidomain scaffolding Mg(2+)-independent protein kinase that catalyzes the phosphotransfer from ATP to proteins such as NRXN1, and plays a role in synaptic transmembrane protein anchoring and ion channel trafficking (PubMed:18423203). ...

    Synonyms: Calcium/calmodulin-dependent serine protein kinase
  9. Target

    Protein S100-B

    go.drugbank.com/bio_entities/BE0001177
    TargetHumans

    Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer (PubMed:20950652, PubMed:6487634). … Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites (By similarity).

    Synonyms: S100 calcium-binding protein BFunction: calcium ion binding
  10. Target

    Protein S100-P

    go.drugbank.com/bio_entities/BE0001191
    TargetHumans

    May function as calcium sensor and contribute to cellular calcium signaling. … In a calcium-dependent manner, functions by interacting with other proteins, such as EZR and PPP5C, and indirectly plays a role in physiological processes like the formation of microvilli in epithelial

    Synonyms: S100 calcium-binding protein P