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Displaying results 81 - 90 of 866 in total
  1. Target

    Baculoviral IAP repeat-containing protein 5

    go.drugbank.com/bio_entities/BE0003408
    TargetHumans

    Multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:20627126, PubMed:21364656, PubMed:25778398, PubMed:28218735, PubMed:9859993). Component of a chromosome passage protein complex (CP...

    Polypeptides: Baculoviral IAP repeat-containing protein 5
  2. Target

    Baculoviral IAP repeat-containing protein 7

    go.drugbank.com/bio_entities/BE0010707
    TargetHumans

    Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control (PubMed:11024045, PubMed:11084335, PubMed:11162435, PubMed:16729033, PubM...

    Polypeptides: Baculoviral IAP repeat-containing protein 7
  3. Drug

    Ixazomib

    go.drugbank.com/drugs/DB09570
    ApprovedInvestigational

    Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor.[A7948] More than 99% of the drug compound is the R-enantiomer.

  4. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Also known as Aspirin, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platele...

    Mixtures: Care One migraine relief, Care One headache relief added strengthProducts: Care One Aspirin
  5. Drug

    Corifollitropin alfa

    go.drugbank.com/drugs/DB09066
    ApprovedInvestigational

    Corifollitropin alfa, also known as _Elonva_ is used in women undergoing fertility treatment to stimulate the development of more than one mature egg (oocyte) at a time in the ovaries. … In July 2014, Merck announced the receipt of a Complete Response Letter (CRL) from the U.S. FDA for its New Drug Application for this drug.

  6. Drug

    Pyridoxine

    go.drugbank.com/drugs/DB00165
    ApprovedInvestigationalNutraceuticalVet approved

    Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine [A32836].

    Mixtures: Cavan One, Folet One
  7. Drug

    Calcium carbonate

    go.drugbank.com/drugs/DB06724
    ApprovedInvestigational

    Calcium carbonate is an inorganic salt used as an antacid. It is a basic compound that acts by neutralizing hydrochloric acid in gastric secretions. Subsequent increases in pH may inhibit the action of pepsin. An increase in bicarbonate ...

    Mixtures: Se-Natal One, Virt-Care OneProducts: Care One Calcium Antacid
  8. Target

    Baculoviral IAP repeat-containing protein 1

    go.drugbank.com/bio_entities/BE0010810
    TargetHumans

    Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...

    Polypeptides: Baculoviral IAP repeat-containing protein 1
  9. Drug

    Capivasertib

    go.drugbank.com/drugs/DB12218
    ApprovedInvestigational

    [A262021] The PIK3/AKT pathway is one of the most commonly activated pathways in breast cancer, mainly through the constitutively active mutation in AKT1, loss of function mutation in PTEN, a negative … November 17th, 2023, capivasertib, under the brand name TRUQAP, was approved by the FDA for the treatment of adult patients HR-positive, HER2-negative locally advanced or metastatic breast cancer with one

  10. Drug

    Imelasomeran

    go.drugbank.com/drugs/DB17090
    ApprovedInvestigational

    Imelasomeran was first approved in Canada on September 1, 2022, as one-half of Moderna's Spikevax Bivalent COVID-19 mRNA vaccine.