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Displaying results 81 - 90 of 10000 in total
  1. Drug

    Dextroamphetamine

    go.drugbank.com/drugs/DB01576
    ApprovedIllicitInvestigational

    Dextroamphetamine is the dextrorotatory enantiomer of amphetamine[A2505]. Dextroamphetamine was approved by the FDA in 2001 for the treatment of attention deficit hyperactivity disorder.[L6010,L52145]

    Mixtures: Mixed Salts of a Single Entity Amphetamine Product XR, Mixed Salts of a Single Entity Amphetamine Product XRCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
  2. Drug

    Selenious acid

    go.drugbank.com/drugs/DB11127
    Approved

    Selenious acid is the acid form of sodium selenite, a form of selenium [L1910]. Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. … Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis [L1921].

    Mixtures: Nutrilite Double X, Vitamins C Plus E W.beta Carotene and SeProducts: Micro Se, Formula-SE
  3. Drug

    Morphine

    go.drugbank.com/drugs/DB00295
    ApprovedInvestigational

    [A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse. … [A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of varying strength such as [codeine], [fentanyl], [methadone], [hydrocodone], [hydromorphone], [meperidine

    Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesSynonyms: (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol, (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol
  4. Drug

    Metoprolol

    go.drugbank.com/drugs/DB00264
    ApprovedInvestigational

    Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [A175162] Metoprolol was developed since 1969 by US Pharmaceutical Holdings I and FDA approved in 1978.[L5527]

    Mixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor Antagonists
  5. Drug

    Flurbiprofen

    go.drugbank.com/drugs/DB00712
    ApprovedInvestigational

    Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity. … Flurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen.

    Mixtures: MULTIFLEX 200/8 MG SR KAPSUL, 14 ADET, MAJEZIK DUO %5 + %0.25 TOPIKAL JEL, 50 GCategories: Cytochrome P-450 Substrates, Non COX-2 selective NSAIDS
  6. Drug

    Theophylline

    go.drugbank.com/drugs/DB00277
    ApprovedInvestigational

    Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD. … Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.

    Mixtures: I D M Expectorant Tab, TUSBRON-A JARABECategories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2D6 Substrates with a Narrow Therapeutic Index
  7. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    Phenol is an antiseptic and disinfectant. It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. … During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.

    Mixtures: Coghlan s Sting Relief, Chapstick Medicated Lip Balm - JarCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Plantago ovata seed

    go.drugbank.com/drugs/DB14585
    ApprovedWithdrawn

    Products: Mucilin Sf, MUCILIN SF
  9. Drug

    Etanercept

    go.drugbank.com/drugs/DB00005
    ApprovedInvestigational

    It is used to treat or manage a variety of inflammatory conditions including rheumatoid arthritis (RA), ankylosing spondylitis (AS), and juvenile idiopathic poly-articular arthritis (JIA). … Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids.

    Products: BENEPALI 50MG ILO I E FER, BENEPALI 50MG ILO I PEN
  10. Drug

    Alprazolam

    go.drugbank.com/drugs/DB00404
    ApprovedIllicitInvestigational

    Alprazolam is a triazolobenzodiazepine indicated for the treatment of anxiety and panic disorders. … [L34783, L34788] It is mainly metabolized by CYP3As and so is contraindicated with CYP3A inhibitors like ketoconazole and itraconazole.

    Mixtures: NEUPAX DUO-SCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-Ring