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Dolutegravir
go.drugbank.com/drugs/DB08930ApprovedInvestigationalDolutegravir is an HIV-1 integrase inhibitor that blocks the strand transfer step of the integration of the viral genome into the host cell (INSTI).
Mixtures: Triumeq PDCategories: P-glycoprotein substratesPanax ginseng fruit
go.drugbank.com/drugs/DB14261InvestigationalIt is not an approved drug.
Products: Ginseng Khan, Korea Gongjin-DanAlteplase
go.drugbank.com/drugs/DB00009ApprovedInvestigationalAlteplase is a recombinant tissue plasminogen activator (rt-PA) used as a thrombolytic agent.[L43125] It cleaves plasminogen to form plasmin, an enzyme involved in the degradation of fibrin clots.
Mixtures: Activase RT-PA, Lysatec RT - PaSynonyms: t-PA, rt-PASodium fluoride
go.drugbank.com/drugs/DB09325ApprovedInvestigationalSodium fluoride is an inorganic chemical compound that is a source of the fluoride ion in many applications, including dental care and radiographic imaging when it is used as [Fluoride ion F-18].
Mixtures: Opalescence PF, Luster Premium White AM/PMProducts: Gel-kam Fluorocare Part A-bubblegum, Gel-kam Fluorocare Part A-mint FlavourRivaroxaban
go.drugbank.com/drugs/DB06228ApprovedInvestigationalRivaroxaban is an anticoagulant and the first orally active direct factor Xa inhibitor. Unlike warfarin, routine lab monitoring of INR is not necessary. … Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. FDA approved on July 1, 2011.
Categories: Cytochrome P-450 Substrates, P-glycoprotein substratesProducts: RIVAROXABAN DR. REDDY'S, Ixobran 15 (Rivaroxaban Tablet Ph Eur 15mg)Ergocalciferol
go.drugbank.com/drugs/DB00153ApprovedInvestigationalNutraceuticalErgocalciferol is an inactivated vitamin D analog.[A177526] It is synthesized by some plants in the presence of UVB light. … These modifications reduce the affinity of ergocalciferol for the vitamin D binding protein resulting in faster clearance, limits its activation, and alters its catabolism.
Synonyms: Vitamin D2, Vitamin D 2Mixtures: Aquasol A & D Drops, Cal/mag 2:1 With DDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. … [A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Van-dorzolamide-timolol, NEFRIDAXEM B+DCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesMethyl aminolevulinate
go.drugbank.com/drugs/DB00992ApprovedInvestigationalMethyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Synonyms: Aminolevulinato de metiloProducts: KRX Aesthetics PD-13 TherapyMethyl salicylate
go.drugbank.com/drugs/DB09543ApprovedInvestigationalVet approvedIt can be manufactured synthetically and it used as a fragrance, in foods, beverages, and liniments. … Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic ester naturally produced by many species of plants, particularly wintergreens.
Mixtures: Kaz Inhalant, Ken- Ku Oil Cap Pancor MasProducts: Veneno de Abeja Aceite De Vibora Brand, Balsamo de Ubre MascuraDiphenhydramine
go.drugbank.com/drugs/DB01075ApprovedInvestigationalWhile its use in allergy therapy can sometimes fall out of favor due to its sedative effect, diphenhydramine has been repurposed for use within many non-prescription over-the-counter sleep aids and cough-and-cold … As histamine receptors exist both peripherally and in the central nervous system, diphenhydramine has been shown to cause sedation due to its competitive antagonism of histamine H1 receptors within the
Mixtures: Au Kah Chuen Fugical, DG Health Ibuprofen PMCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates