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Bivalirudin
go.drugbank.com/drugs/DB00006ApprovedInvestigationalBivalirudin is a synthetic 20 residue peptide (thrombin inhibitor) which reversibly inhibits thrombin.
Products: OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 10 ADET, OBIVADIN 250 MG IV ENJEKSIYON/INFÜZYON IÇIN LIYOFILIZE TOZ, 1 ADETFebuxostat
go.drugbank.com/drugs/DB04854ApprovedInvestigational[A39743] In early 2008, febuxostat was granted marketing authorization by the European Commission for the treatment of chronic hyperuricemia and gout. … Febuxostat works by inhibiting the activity of an enzyme that is responsible for the synthesis of uric acid, thereby reducing serum uric acid levels.
Categories: Heterocyclic Compounds, 1-RingProducts: ADENURIC 120 MG, GOUTEX 120 MGEtoricoxib
go.drugbank.com/drugs/DB01628ApprovedInvestigationalWithdrawnIt is approved in more than 60 countries worldwide but not in the US.
Categories: Heterocyclic Compounds, 1-RingProducts: AUXIB (120 MG), ETOX 120 MGAmphetamine
go.drugbank.com/drugs/DB00182ApprovedIllicitInvestigationalAmphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs. … Amphetamine, with the chemical formula alpha-methylphenethylamine, was discovered in 1910 and first synthesized by 1927.
Synonyms: rac-(2R)-1-phenylpropan-2-amine, 1-phenyl-2-aminopropaneValdecoxib
go.drugbank.com/drugs/DB00580ApprovedWithdrawnValdecoxib was removed from the Canadian, U.S., and E.U. markets in 2005 due to concerns about a possible increased risk of heart attack and stroke.
Categories: Heterocyclic Compounds, 1-RingProducts: BEXTRA ® 10 MG TABLETAS RECUBIERTAS, VALDYNE 40 MG TABLETAS RECUBIERTASTetryzoline
go.drugbank.com/drugs/DB06764Approved[A231769] Available since the 1950s, tetryzoline is a selective α<sub>1</sub>-receptor agonist [A231774] that is used as an ocular and nasal decongestant.
Mixtures: EFEMOLINE 5 ML DAMLA, DG Health Sterile Advanced Relief EyeCategories: Adrenergic alpha-1 Receptor Agonists, Heterocyclic Compounds, 1-RingCapecitabine
go.drugbank.com/drugs/DB01101ApprovedInvestigationalCapecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, wh...
Categories: Heterocyclic Compounds, 1-RingSynonyms: pentyl 1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-1,2-dihydro-2-oxo-4-pyrimidinecarbamate, Pentyl [1-(5-deoxy-β-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamateDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[L11377] It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes.
Mixtures: Dorzolamid + Timolol 1A Pharma 20 mg/ml + 5 mg/ml - Augentropfen, Lösung, DUOSOPT FREE 20 MG+5 MG/ML GÖZ DAMLASI, ÇÖZELTİ, 60 ADETCategories: Heterocyclic Compounds, 1-RingMeropenem
go.drugbank.com/drugs/DB00760ApprovedInvestigationalMeropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death. … The treatment aims to resolve infection-related symptoms and achieve negative urine culture, where the infections are proven or strongly suspected to be caused by susceptible bacteria.
Synonyms: (4R,5S,6S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio}-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acidProducts: MEROZAN 1 G ENJEKTABL TOZ İÇEREN FLAKON, 10 ADET, MEROSID 500 MG IV ENJEKTABL TOZ ICEREN 1 FLAKONOxymetazoline
go.drugbank.com/drugs/DB00935ApprovedInvestigational[L15062] As an effective decongestant, oxymetazoline is available in over-the-counter intranasal sprays used to relieve nasal and sinus congestion caused by a wide variety of conditions, such as common … Oxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AgonistsSynonyms: 3-[(4,5-dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethylphenol