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Deferoxamine
go.drugbank.com/drugs/DB00746ApprovedInvestigationalIt forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Categories: Compounds used in a research, industrial, or household settingProducts: DESFERAL 500 MG IM/IV/SC ENJEKSİYON İÇİN LİYOFİLİZE TOZ İÇEREN FLAKON, 10 ADET, Desferal 500 mg - TrockenstechampullenFlunarizine
go.drugbank.com/drugs/DB04841ApprovedInvestigationalIt is effective in the prophylaxis of migraine, occlusive peripheral vascular disease, vertigo of central and peripheral origin, and as an adjuvant in the therapy of epilepsy. … Flunarizine is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 SubstratesProducts: FLUI-DEX 10 MG, FLUNARIZINA 10 MGMacitentan
go.drugbank.com/drugs/DB08932ApprovedInvestigationalMacitentan differs from its predecessor [bosentan] in part due to its lower risk of hepatotoxicity. … Macitentan is a dual endothelin receptor antagonist used in the treatment of pulmonary arterial hypertension (PAH).[L35890] It was first approved by the FDA in 2013.
Mixtures: OPSYNVI® (MACITENTAN/TADALAFILO) 10MG/40 MG TABLETAS RECUBIERTASCategories: Endothelin A Receptor Antagonists, Cytochrome P-450 SubstratesClemastine
go.drugbank.com/drugs/DB00283ApprovedInvestigationalAn ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Mixtures: Tavist-D TabletsCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … [A253717, L43652] Because CTLA-4 is an immune checkpoint that plays a vital role in regulating T cell-mediated immune response, tremelimumab is considered an immune checkpoint inhibitor, which is an emerging
Products: Imjudo 300 mg/15 ml İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo Concentrate for Solution for Intravenous Infusion 20 mg/mLTolterodine
go.drugbank.com/drugs/DB01036ApprovedInvestigationalTolterodine is an antimuscarinic drug that is used to treat urinary incontinence. Tolterodine acts on M2 and M3 subtypes of muscarinic receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: TOXTREX 4 MG CÁPSULAS DE LIBERACIÓN EXTENDIDA, TOXTREX® 2 MG CÁPSULAS DE LIBERACIÓN EXTENDIDALixisenatide
go.drugbank.com/drugs/DB09265ApprovedInvestigationalIt is sold by Sanofi-Aventis under the brand name Adlyxin in the US[L763] and Lyxumia in the EU.[L764] Adlyxin recieved FDA approval July 28, 2016.[L763] … Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist used in the treatment of type II diabetes mellitus (T2DM).
Mixtures: SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM, SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 3 KALEMCategories: Receptors, G-Protein-CoupledDaunorubicin
go.drugbank.com/drugs/DB00694ApprovedInvestigationalA very toxic anthracycline aminoglycoside antineoplastic isolated from Streptomyces peucetius and others, used in treatment of leukemia and other neoplasms.
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: (8S-cis)-8-acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyrannosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-napthacenedioneChloroprocaine
go.drugbank.com/drugs/DB01161ApprovedInvestigational[A252952] Chloroprocaine can be given as an injection, and is available in formulations with and without methylparaben as a preservative. … Chloroprocaine is an ester local anesthetic commonly available in its salt form, chloroprocaine hydrochloride.
Products: Ampres 10 mg/ml Injektionslösung, Ampres 20 mg/ml InjektionslösungAcebutolol
go.drugbank.com/drugs/DB01193ApprovedInvestigationalThe drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action. … A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsProducts: APO-ACEBUTOLOL TABLET 100 mg, Nu-acebutolol - Tab 100mg