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Displaying results 891 - 900 of 6831 in total
  1. Drug

    Trovafloxacin

    go.drugbank.com/drugs/DB00685
    ApprovedWithdrawn

    It was shown to be more effective against Gram-positive bacteria than Gram-negative bacteria when compared to previous fluoroquinolones. … Due to its hepatotoxic potential, trovafloxacin was withdrawn from the market.

  2. Indication

    Traumatic Brain Injury (TBI)

    go.drugbank.com/conditions/DBCOND0047292
    Drugs: Choline alfoscerate
    Synonyms: Dementia due to head trauma, [X]Injuries to the head (disorder)
  3. Drug

    Sulfamethoxazole

    go.drugbank.com/drugs/DB01015
    ApprovedInvestigational

    [L11830] It is generally given in combination with [trimethoprim], which inhibits a sequential step in bacterial folic acid synthesis - these agents work synergistically to block two consecutive steps … in the biosynthesis of nucleic acids and proteins which are necessary for bacterial growth and division, and using them in conjunction helps to slow the development of bacterial resistance.

    Mixtures: TS-BAC, TS-BAC
  4. Indication

    Dysuria

    go.drugbank.com/conditions/DBCOND0004536
    Drugs: Flavoxate · L-tartaric acid · Saw palmetto
    Synonyms: Painful urging to urinate, Painful urging to urinate (finding)
  5. Drug

    Netilmicin

    go.drugbank.com/drugs/DB00955
    Approved

    Netilmicin is a semisynthetic 1-N-ethyl derivative of sisomycin, an aminoglycoside antibiotic with action similar to gentamicin, but less ear and kidney toxicity. … Netilmicin inhibits protein synthesis in susceptible organisms by binding to the bacterial 30S ribosomal subunit and interfering with mRNA binding and the acceptor tRNA site.

  6. Drug

    Carbidopa

    go.drugbank.com/drugs/DB00190
    ApprovedInvestigational

    [L5110] On the other hand, the combination treatment of carbidopa/levodopa was originally developed by Watson Labs but the historical information by the FDA brings back to the approval of this combination … Due to its activity, carbidopa is always administered concomitantly with [levodopa].

    Mixtures: DOPADEX SR 50 MG/200 MG UZATILMIŞ SALIMLI TABLET,100 TB, DOPADEX SR 25 MG/100 MG UZATILMIŞ SALIMLI TABLET ,100 TB
  7. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    Arbutin was shown to be less cytotoxic to melanocytes in culture compared to [DB09526] [A32942].

    Mixtures: Dr G Whitening REFORMER by EGF, Dr G Whitening FORTIFIER by EGFSynonyms: hydroquinone O-β-D-glucopyranoside, Hydroquinone-O-beta-D-glucopyranoside
  8. Drug

    Meradimate

    go.drugbank.com/drugs/DB11096
    Approved

    [T200] It is currently required to be named as meradimate in all FDA approved OTC products. Meradimate is approved by the FDA and Health Canada to be used as an ingredient in sunblocking products.

    Mixtures: Body Armor Sun 'n Bug BlockSynonyms: Menthyl-O-aminobenzoate
  9. Drug

    Phenol

    go.drugbank.com/drugs/DB03255
    ApprovedInvestigational

    It is active against a wide range of micro-organisms including some fungi and viruses, but is only slowly effective against spores. Phenol has been used to disinfect skin and to relieve itching. … During the second world war, phenol injections were used as a means of execution by the Nazis. Phenol is a toxic compound whose vapours are corrosive to the skin, eyes, and respiratory tract.

    Mixtures: EGOPSORYL TA GEL, EGOPSORYL TA GEL
  10. Drug

    Nimodipine

    go.drugbank.com/drugs/DB00393
    ApprovedInvestigational

    Nimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm. … It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation.