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Displaying results 891 - 900 of 10000 in total
  1. Drug

    Apramycin

    go.drugbank.com/drugs/DB04626
    InvestigationalVet approved

    Apramycin is a structurally unique antibiotic that contains a bicyclic sugar moiety and a monosubstituted deoxystreptamine. It is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.

    Synonyms: 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine, 4-O-(3α-amino-6α-((4-amino-4-deoxy-α-D-glucopyranosyl)oxy)-2,3,4,5aβ,6,7,8,8aα-octahydro-8β-hydroxy-7β-(methylamino)pyrano(3,2-b)pyran-2α-yl)-2-deoxy-D-streptamineProducts: TP-APRA 500 WSP ApramycinSulphate 500mg/g Water Soluble Powder
  2. Drug

    Technetium Tc-99m

    go.drugbank.com/drugs/DB14227
    Investigational

    Technetium-99m is the metastable isotope of technetium. It is commonly symbolized as 99mTc and used in the area of medical diagnosis. Technetium-99m is the most commonly used medical radioisotope.

    Synonyms: Tc 99, Technetium Tc 99mProducts: TECHNECIUM TC 99M GENERADOR
  3. Drug

    Chlorpheniramine

    go.drugbank.com/drugs/DB01114
    ApprovedInvestigational

    One of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine. … A histamine H1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. It has also been used in veterinary applications.

    Mixtures: Pancold S, Stona-SCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Cytochrome P-450 Substrates
  4. Drug

    Hydrogen peroxide

    go.drugbank.com/drugs/DB11091
    ApprovedInvestigationalVet approved

    Hydrogen peroxide is the simplest peroxide with a chemical formula H2O2. … Hydrogen peroxide is an unstable compound in the presence of a base or catalyst, and is typically stored with a stabilizer in a weakly acidic solution.

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting
  5. Indication

    Inflammatory Muscle Disease

    go.drugbank.com/conditions/DBCOND0155571
    Drugs: Acetaminophen · Acetylsalicylic acid · Azapropazone · Diazepam · Diclofenac · Methyl salicylate +2 more
    Synonyms: Inflammation;Muscle(S)
  6. Drug

    Paclitaxel

    go.drugbank.com/drugs/DB01229
    ApprovedInvestigationalVet approved

    Paclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. … Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2C8 Substrates with a Narrow Therapeutic IndexSynonyms: 5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine, Taxol A
  7. Drug

    Dimenhydrinate

    go.drugbank.com/drugs/DB00985
    ApprovedInvestigational

    effects are thought to be produced by 8-chlorotheophylline's adenosine receptor blockade. … [A233130] Dimenhydrinate, also known as B-dimethylaminoethyl benzohydrol ether 8-chlorotheophyllinate, is indicated to prevent nausea, vomiting, and dizziness caused by motion sickness.

    Categories: Heterocyclic Compounds, 2-RingSynonyms: 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1), N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate
  8. Drug

    Diclofenac

    go.drugbank.com/drugs/DB00586
    ApprovedInvestigationalVet approved

    [label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. … It is often used in combination with [misoprostol] to prevent NSAID-induced gastric ulcers.

    Mixtures: DICLOFENACO SÓDICO 100 MG - HIDROXIDO DE ALUMINIO GEL EQUIVALENTE A200 MG, DICLOFENACO SÓDICO 100 MG - HIDROXIDO DE ALUMINIO GEL EQUIVALENTE A200 MGCategories: Cyclooxygenase-2 (COX-2) Inhibitors, P-glycoprotein inducers
  9. Target

    Mitochondrial peptide methionine sulfoxide reductase

    go.drugbank.com/bio_entities/BE0000170
    TargetEnzymeHumans

    Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation (PubMed:10452521, PubMed:12039877). Plays a...

    Synonyms: Peptide-methionine (S)-S-oxide reductase, Protein-methionine-S-oxide reductaseFunction: L-methionine (S)-S-oxide reductase activity
  10. Drug

    Insulin glargine

    go.drugbank.com/drugs/DB00047
    ApprovedInvestigational

    Insulin glargine is also available as the biosimilar, or "follow-on" product, Basaglar in the US and as Abasaglar in the EU. … Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal muscle.

    Mixtures: SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM, SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEMCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers