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Bromocriptine
go.drugbank.com/drugs/DB01200ApprovedInvestigationalWithdrawnBromocriptine mesylate is a semisynthetic ergot alkaloid derivative with potent dopaminergic activity.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 2-bromo-α-ergokryptin, 2-bromo-α-ergocryptineRifapentine
go.drugbank.com/drugs/DB01201ApprovedInvestigationalRifapentine is an antibiotic drug used in the treatment of tuberculosis. It inhibits DNA-dependent RNA polymerase activity in susceptible cells. Specifically, it interacts with bacterial RNA polymerase but does not inhibit the mammalian ...
Synonyms: 3-(((4-Cyclopentyl-1-piperazinyl)imino)methyl)rifamycinCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersMitoxantrone
go.drugbank.com/drugs/DB01204ApprovedInvestigationalAn anthracenedione-derived antineoplastic agent.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexSynonyms: 1,4-Bis(2-(2-hydroxyethylamino)ethyl)amino)-5,8-dihydroxyanthraquinoneLomustine
go.drugbank.com/drugs/DB01206ApprovedInvestigationalAn alkylating agent of value against both hematologic malignancies and solid tumors.
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: 1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea, N-(2-chloroethyl)-N'-cyclohexyl-N-nitrosoureaRidogrel
go.drugbank.com/drugs/DB01207ExperimentalRidogrel is a dual action drug useful for the prevention of systemic thrombo-embolism and as an adjunctive agent to thrombolytic therapy in acute myocardial infarction.
Categories: Heterocyclic Compounds, 1-Ring, Thromboxane-A Synthase, antagonists & inhibitorsDezocine
go.drugbank.com/drugs/DB01209ApprovedInvestigationalDezocine is a partial opiate drug and is used for pain management. … Dezocine is a very effective alternative to fentanyl when administered during outpatient laparoscopy, although is associated with an increased incidence of postoperative nausea.
Synonyms: (−)-13β-amino-5,6,7,8,9,10,11α,12-octahydro-5α-methyl-5,11-methanobenzocyclodecen-3-olLevobunolol
go.drugbank.com/drugs/DB01210ApprovedA nonselective beta-adrenoceptor antagonist used in the treatment of glaucoma.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesSynonyms: (S)-5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-1(2H)-naphthalenoneHalofantrine
go.drugbank.com/drugs/DB01218ApprovedWithdrawnHalofantrine is an antimalarial. It belongs to the phenanthrene class of compounds that includes quinine and lumefantrine. It appears to inhibit polymerisation of heme molecules (by the parasite enzyme "heme polymerase"), resulting in th...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesRifaximin
go.drugbank.com/drugs/DB01220ApprovedInvestigationalsyndrome (IBS-D) in adult women and men. … Rifaximin is a semisynthetic, rifamycin-based non-systemic antibiotic, meaning that the drug will not pass the gastrointestinal wall into the circulation as is common for other types of orally administered
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersSynonyms: Rifamycin L 105, Rifamycin L 105SVAminophylline
go.drugbank.com/drugs/DB01223ApprovedInvestigationalAminophylline is a drug combination that contains theophylline and ethylenediamine in a 2:1 ratio. … Once in the body, theophylline is released and acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator.
Categories: Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP2E1 Substrates with a Narrow Therapeutic IndexProducts: อมิโนฟิลลีน 1 1/2 เกรน, DRAFILYN Z