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Displaying results 911 - 920 of 2674 in total
  1. Target

    Muscle, skeletal receptor tyrosine-protein kinase

    go.drugbank.com/bio_entities/BE0009491
    TargetHumans

    Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle (PubMed:25537362

    Polypeptides: Muscle, skeletal receptor tyrosine-protein kinaseSynonyms: Muscle-specific kinase receptor, Muscle-specific tyrosine-protein kinase receptor
  2. Target

    IgG receptor FcRn large subunit p51

    go.drugbank.com/bio_entities/BE0010182
    TargetTransporterCarrierHumans

    Cell surface receptor that transfers passive humoral immunity from the mother to the newborn.

    Polypeptides: IgG receptor FcRn large subunit p51Synonyms: Neonatal Fc receptor, IgG Fc fragment receptor transporter alpha chain
  3. Target

    Receptor-type tyrosine-protein phosphatase C

    go.drugbank.com/bio_entities/BE0010406
    TargetHumans

    Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor (PubMed:35767951). Acts as a positive regulator of T-cell coactivation upon binding to DPP4. … Interacts with CLEC10A at antigen presenting cell-T cell contact; CLEC10A on immature dendritic cells recognizes Tn antigen-carrying PTPRC/CD45 receptor on effector T cells and modulates T cell activation

    Polypeptides: Receptor-type tyrosine-protein phosphatase C
  4. Target

    Killer cell immunoglobulin-like receptor 2DL1

    go.drugbank.com/bio_entities/BE0010669
    TargetHumans

    Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis

    Polypeptides: Killer cell immunoglobulin-like receptor 2DL1Synonyms: p58 NK receptor CL-42/47.11, p58.1 MHC class-I-specific NK receptor
  5. Target

    Baculoviral IAP repeat-containing protein 1

    go.drugbank.com/bio_entities/BE0010810
    TargetHumans

    Anti-apoptotic protein which acts by inhibiting the activities of CASP3, CASP7 and CASP9. Can inhibit the autocleavage of pro-CASP9 and cleavage of pro-CASP3 by CASP9. Capable of inhibiting CASP9 autoproteolysis at 'Asp-315' and decreasi...

    Polypeptides: Baculoviral IAP repeat-containing protein 1
  6. Target

    Tyrosine-protein kinase transmembrane receptor ROR2

    go.drugbank.com/bio_entities/BE0010827
    TargetHumans

    May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443) … Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity).

    Polypeptides: Tyrosine-protein kinase transmembrane receptor ROR2Synonyms: Neurotrophic tyrosine kinase, receptor-related 2
  7. Target

    Killer cell immunoglobulin-like receptor 2DL2

    go.drugbank.com/bio_entities/BE0010848
    TargetHumans

    Receptor on natural killer (NK) cells for HLA-Cw1, 3, 7, and 8 allotypes. Inhibits the activity of NK cells thus preventing cell lysis

    Polypeptides: Killer cell immunoglobulin-like receptor 2DL2Synonyms: p58 NK receptor CL-43, p58 natural killer cell receptor clone CL-43
  8. Target

    Killer cell immunoglobulin-like receptor 3DL2

    go.drugbank.com/bio_entities/BE0010849
    TargetHumans

    Receptor on natural killer (NK) cells and T cells for MHC class I molecules (PubMed:24018270, PubMed:28636952). … Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity (PubMed:26928464)

    Polypeptides: Killer cell immunoglobulin-like receptor 3DL2Synonyms: p70 NK receptor CL-5, p70 natural killer cell receptor clone CL-5
  9. Target

    Interleukin-22 receptor subunit alpha-1

    go.drugbank.com/bio_entities/BE0016650
    TargetHumans

    Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. … Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation.

    Polypeptides: Interleukin-22 receptor subunit alpha-1Synonyms: IL-22 receptor subunit alpha-1, Cytokine receptor class-II member 9
  10. Target

    Taste receptor type 2 member 3

    go.drugbank.com/bio_entities/BE0023234
    TargetHumans

    Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5

    Polypeptides: Taste receptor type 2 member 3Function: bitter taste receptor activity