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Lymphatic vessel endothelial hyaluronic acid receptor 1
go.drugbank.com/bio_entities/BE0010044TargetHumansLigand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding ...
Polypeptides: Lymphatic vessel endothelial hyaluronic acid receptor 1Synonyms: Hyaluronic acid receptorNuclear receptor subfamily 4immunitygroup A member 1
go.drugbank.com/bio_entities/BE0010494TargetHumansOrphan nuclear receptor. Binds the NGFI-B response element (NBRE) 5'-AAAGGTCA-3' (PubMed:18690216, PubMed:8121493, PubMed:9315652).
Polypeptides: Nuclear receptor subfamily 4immunitygroup A member 1Synonyms: Testicular receptor 3, Orphan nuclear receptor HMRTumor necrosis factor receptor superfamily member 18
go.drugbank.com/bio_entities/BE0010519TargetHumansReceptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death.
Polypeptides: Tumor necrosis factor receptor superfamily member 18Synonyms: Activation-inducible TNFR family receptorLow-density lipoprotein receptor-related protein 6
go.drugbank.com/bio_entities/BE0012061TargetHumansComponent of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes (PubMed:11357136, PubMed:11448771
Polypeptides: Low-density lipoprotein receptor-related protein 6Tyrosine-protein phosphatase non-receptor type 2
go.drugbank.com/bio_entities/BE0012706TargetHumansNon-receptor type tyrosine-specific phosphatase that dephosphorylates receptor protein tyrosine kinases including INSR, EGFR, CSF1R, PDGFR. … May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of the hepatocyte growth factor receptor MET. Also plays an important role in glucose homeostasis.
Polypeptides: Tyrosine-protein phosphatase non-receptor type 2Tumor necrosis factor receptor superfamily member EDAR
go.drugbank.com/bio_entities/BE0021253TargetHumansReceptor for EDA isoform A1, but not for EDA isoform A2. Mediates the activation of NF-kappa-B and JNK. May promote caspase-independent cell death
Polypeptides: Tumor necrosis factor receptor superfamily member EDARSynonyms: EDA-A1 receptor, Ectodysplasin-A receptorT cell receptor beta variable 6-5
go.drugbank.com/bio_entities/BE0021562TargetHumansV region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447).
Polypeptides: T cell receptor beta variable 6-5High affinity immunoglobulin epsilon receptor subunit alpha
go.drugbank.com/bio_entities/BE0000015TargetHumansHigh-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells.
Polypeptides: High affinity immunoglobulin epsilon receptor subunit alphaSynonyms: IgE Fc receptor subunit alphaHigh affinity immunoglobulin gamma Fc receptor I
go.drugbank.com/bio_entities/BE0000710TargetCarrierHumansHigh affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.
Polypeptides: High affinity immunoglobulin gamma Fc receptor ISynonyms: IgG Fc receptor IGamma-aminobutyric acid receptor subunit alpha-6
go.drugbank.com/bio_entities/BE0000764TargetHumansAlpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:8632757). GABA-gated chloride channels, also named GABA(A) receptors (G...
Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-6Synonyms: GABA(A) receptor subunit alpha-6