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Glutathione synthetase
go.drugbank.com/bio_entities/BE0000185TargetHumansCatalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner (PubMed:7646467, PubMed:9215686). Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in li...
Synonyms: GSH-SVitronectin
go.drugbank.com/bio_entities/BE0001068TargetHumansVitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adh...
Synonyms: S-proteinAnamorsin homolog
go.drugbank.com/bio_entities/BE0009259TargetPlasmodium falciparum (isolate 3D7)Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. … Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the cytosolic Fe-S scaffold complex.
Synonyms: Fe-S cluster assembly protein DRE2 homologDiclofenac
go.drugbank.com/drugs/DB00586ApprovedInvestigationalVet approved[label] NSAIDs inhibit cyclooxygenase (COX)-1 and-2 which are the enzyme responsible for producing prostaglandins (PGs). PGs contribute to inflammation and pain signalling. … It is often used in combination with [misoprostol] to prevent NSAID-induced gastric ulcers.
Mixtures: DICLOFENACO SÓDICO 100 MG - HIDROXIDO DE ALUMINIO GEL EQUIVALENTE A200 MG, DICLOFENACO SÓDICO 100 MG - HIDROXIDO DE ALUMINIO GEL EQUIVALENTE A200 MGCategories: Cyclooxygenase-2 (COX-2) Inhibitors, P-glycoprotein inducersPuromycin-sensitive aminopeptidase
go.drugbank.com/bio_entities/BE0003419TargetHumansAminopeptidase with broad substrate specificity for several peptides. Involved in proteolytic events essential for cell growth and viability. May act as regulator of neuropeptide activity. Plays a role in the antigen-processing pathway f...
Synonyms: AAP-SInsulin glargine
go.drugbank.com/drugs/DB00047ApprovedInvestigationalInsulin glargine is also available as the biosimilar, or "follow-on" product, Basaglar in the US and as Abasaglar in the EU. … Insulin is released from the pancreas following a meal to promote the uptake of glucose from the blood into internal organs and tissues such as the liver, fat cells, and skeletal muscle.
Mixtures: SOLİQUA SOLOSTAR 100 U/ML + 33 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEM, SOLİQUA SOLOSTAR 100 U/ML + 50 MCG/ML SC ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR KALEM, 5 KALEMCategories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersCetirizine
go.drugbank.com/drugs/DB00341ApprovedInvestigationalOne of the most common uses for this drug is for a condition called _allergic rhinitis_. … The prevalence of allergic rhinitis in the United States is about 15% according to physician diagnoses, and up to 30%, according to self-reported nasal symptoms.
Mixtures: GRIFANTIL T JARABE, Kirkland Signature Aller Tec DCategories: P-glycoprotein inhibitors, P-glycoprotein substratesParkinson's Disease (PD)
go.drugbank.com/conditions/DBCOND0053495Synonyms: Parkinson&Amp;#39;s DiseaseDipropylene glycol
go.drugbank.com/drugs/DB14140InvestigationalSynonyms: 4-Oxa-2,6-heptandiol, 1,1'-Oxybis(2-propanol)Products: Abelia green tea energy mask, Dr.g A-clear Balancing MoisturizerLaminin subunit alpha-1
go.drugbank.com/bio_entities/BE0002108TargetHumansBinding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. As a li...
Synonyms: S-LAM alpha, S-laminin subunit alpha