Search
Osilodrostat
go.drugbank.com/drugs/DB11837ApprovedInvestigationalOsilodrostat is manufactured by Novartis under the brand name Isturisa. … Cushing's disease),[A191850] and was granted FDA approval and Orphan Drug designation in the US in March 2020 for the same indication.[L12162]
Iptacopan
go.drugbank.com/drugs/DB16200ApprovedInvestigational[A262581] On December 6th, 2023, Iptacopan under the brand name Fabhalta was approved by the FDA for the treatment of adults with PNH. … Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor
Categories: Compounds used in a research, industrial, or household settingFlavin mononucleotide
go.drugbank.com/drugs/DB03247ApprovedInvestigational[L54226] In addition to its systemic use as a means of riboflavin supplementation, a topical ophthalmic preparation of FMN was approved by the FDA in October 2025 for use as a photoenhancer in epithelium-on … [A274616,L54226] FMN is composed of an isoalloxazine ring - which serves as the active redox center - attached to a ribityl phosphate chain.
Mixtures: Alsimine W Vitamins A D, BumP DHAElasomeran
go.drugbank.com/drugs/DB15654ApprovedInvestigationalThe Moderna COVID-19 Vaccine (mRNA-1273; Elasomeran) is a novel mRNA-based vaccine encapsulated in a lipid nanoparticle that encodes for a full-length pre-fusion stabilized spike (S) protein of severe … Coronavirus disease 2019 (COVID-19) is a highly contagious infectious disease caused by the novel coronavirus, SARS-CoV-2, leading to a respiratory illness alongside other complications.
Mixtures: Spikevax Bivalent (original / Omicron Ba.4/5)Peginterferon beta-1a
go.drugbank.com/drugs/DB09122ApprovedInvestigational[A176474,L5792] Peginterferon beta-1a is an interferon therapy used for the management of relapsing forms of MS. … It was originally approved by the FDA in 2014 for subcutaneous use, and was approved for intramuscular use in January 2021.
Categories: peginterferon beta-1a, Compounds used in a research, industrial, or household settingSynonyms: PEG IFN-beta-1a, Peginterferon beta-1aInclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigationalInclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density … A225953,A225958] Lowering circulating plasma LDL-C levels offers an additional benefit of reducing the risk of cardiovascular disease (CVD) and improving cardiovascular outcomes, as hypercholesterolemia is a
Categories: Compounds used in a research, industrial, or household settingCitric acid
go.drugbank.com/drugs/DB04272ApprovedInvestigationalNutraceuticalVet approvedCitric acid is one of the active ingredients in Phexxi, a non-hormonal contraceptive agent that was approved by the FDA on May 2020. … A key intermediate in metabolism. It is an acid compound found in citrus fruits. The salts of citric acid (citrates) can be used as anticoagulants due to their calcium-chelating ability.
Mixtures: A-C-D Solution, Sal de Uvas PicotCategories: Compounds used in a research, industrial, or household settingFinasteride
go.drugbank.com/drugs/DB01216ApprovedInvestigational[L6244] Finasteride is commonly marketed under the brand names Propecia and Proscar to be used aloneo or in combination with [doxazosin], an alpha-blocker. … [L6244,L10565] In 1998, it was approved by the FDA to treat male pattern hair loss.
Products: Sandoz Finasteride A, FINASTERID 1A PHARMA 5MGIcosapent ethyl
go.drugbank.com/drugs/DB08887ApprovedInvestigationalNutraceuticalFDA approved on July 26, 2012. … It is used as an adjunct therapy for severe hypertriglyceridemia (TG levels > 500 mg/dL) and to reduce the risk of cardiovascular events in certain patients with elevated triglycerides.
Peptidoglycan D,D-transpeptidase MrdA
go.drugbank.com/bio_entities/BE0004648TargetPseudomonas aeruginosaCatalyzes cross-linking of the peptidoglycan cell wall.
Synonyms: penA