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Mercaptopurine
go.drugbank.com/drugs/DB01033ApprovedInvestigationalIt interferes with nucleic acid synthesis by inhibiting purine metabolism and is used, usually in combination with other drugs, in the treatment of or in remission maintenance programs for leukemia. … An antimetabolite antineoplastic agent with immunosuppressant properties.
Synonyms: 6 MP, 6-MPCategories: Heterocyclic Compounds, 2-RingEribulin
go.drugbank.com/drugs/DB08871ApprovedInvestigationalEribulin is also being investigated for use in the treatment of advanced solid tumors [A7439]. … Eribulin is a microtubule inhibitor indicated for the treatment of patients with metastatic breast cancer who have previously received at least two chemotherapeutic regimens for the treatment of metastatic
Products: ERIBULINA EG, HALAVEN 0.5 mg/ml solution for injectionAntithymocyte immunoglobulin (rabbit)
go.drugbank.com/drugs/DB00098ApprovedInvestigationalThe most common mode of action of Thymoglobulin is via selective depletion of T-cells. … Thymoglobulin is a polyclonal antibody that suppresses certain types of immune cells responsible for acute organ rejection in transplant patients.
Synonyms: Lapine T-lymphocyte immune globulin, Anti-T-lymphocyte immune globulin, rabbitCategories: Immunoglobulin G, Increased T Lymphocyte DestructionCinacalcet
go.drugbank.com/drugs/DB01012ApprovedInvestigationalIt is used to treat hyperparathyroidism due to parathyroid tumours or renal failure. … Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineMelphalan
go.drugbank.com/drugs/DB01042ApprovedInvestigational[L40928] It was first synthesized in the early 1950s by substituting L-phenylalanine for the methyl group on nitrogen mustard. … [A261150, A261155] Melphalan is used in the treatment of multiple myeloma and ovarian carcinoma.[L40928] It is also used for high-conditioning before hematopoietic stem cell transplant.
Synonyms: p-N,N-bis(2-chloroethyl)amino-L-phenylalanine, p-N-Bis(2-chloroethyl)amino-L-phenylalanineProducts: ALKERAN FOR INJECTION 50 mg/vial, ALKERAN 2 MG TABLET, 25 ADETPimozide
go.drugbank.com/drugs/DB01100ApprovedA diphenylbutylpiperidine that is effective as an antipsychotic agent and as an alternative to haloperidol for the suppression of vocal and motor tics in patients with Tourette syndrome.
Categories: Heterocyclic Compounds, 2-Ring, Serotonin 5-HT2 Receptor AntagonistsProducts: NOROFREN 2 MG TABLET, 10 ADET, NOROFREN 2 MG TABLET, 500 ADETIdarucizumab
go.drugbank.com/drugs/DB09264Approved, concomitant NSAID or warfarin use, etc). … Idarucizumab is a humanized monoclonal antibody fragment (Fab) derived from an immunoglobulin G1 isotype molecule that binds to and inactivates the oral anticoagulant dabigatran, thereby reversing its
Products: PRAXBİND 50 MG/ML ENJEKSİYONLUK/İNFÜZYONLUK ÇÖZELTİ, 2 ADET, PRAXBIND Solution for Injection/Infusion 50 mg/mlFlumazenil
go.drugbank.com/drugs/DB01205ApprovedInvestigationalFumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine … receptor complex, thereby reversing the effects of benzodiazepine on the central nervous system.
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingProducts: ANEXATE 1 MG/10 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADET, ANEXATE 0,5 MG/5 ML IV ENJ. ICIN COZ. ICEREN AMPUL, 5 ADETClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigationalin recent MI, stroke, or established peripheral arterial disease,[L7213] It has been shown to be superior to [aspirin] in reducing cardiovascular outcomes in patients with cardiovascular disease and … [A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and
Mixtures: KLOGEL-A 75/100 MG KAPSUL, 30 ADET, KLOGEL-A 75/100 MG KAPSUL, 90 ADETCategories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesTolevamer
go.drugbank.com/drugs/DB01344ApprovedIt may be taken orally or by rectum, as an enema, and functions as a potassium-binding resin in the intestines. … It is also an effective topical microbicide and spermicide, inhibiting the genital transfection of, among others, HIV.
Categories: Compounds used in a research, industrial, or household settingSynonyms: poly(styrene-4-sulfonic acid)