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Acetic acid
go.drugbank.com/drugs/DB03166ApprovedInvestigationalAcetic acid is a product of the oxidation of ethanol and of the destructive distillation of wood. It is used locally, occasionally internally, as a counterirritant and also as a reagent. … (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.
Mixtures: ICEKING Skin Expert Anti-onychomycosis Gel, POLYLAB T-EUSOL (SOLUTION A & B)Categories: Compounds used in a research, industrial, or household settingHydralazine
go.drugbank.com/drugs/DB01275ApprovedInvestigationalOriginally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed. … [A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of heart failure.
Mixtures: Ser-Ap-Es, Ser-AP-ES TabIxazomib
go.drugbank.com/drugs/DB09570ApprovedInvestigationalIxazomib is a reversible proteasome inhibitor. Because it is a modified peptide boronic acid with one chiral center,[A264329] it is considered a boronate proteasome inhibitor. … [L51244] It was also investigated in other hematological malignancies as well as other conditions, such as systemic light chain (AL) amyloidosis, graft-versus-host disease, and lupus nephritis.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 Substrates with a Narrow Therapeutic IndexMicafungin
go.drugbank.com/drugs/DB01141ApprovedInvestigationalMicafungin is an antifungal drug. … It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
Empagliflozin
go.drugbank.com/drugs/DB09038ApprovedInvestigational[A203501] Attempts at overcoming these limitations first saw the development of O-glucoside analogs of phlorizin (e.g. … [A203453] It is used clinically as an adjunct to diet and exercise, often in combination with other drug therapies,[L13673,L13679,L11479] for the management of type 2 diabetes mellitus.
Reserpine
go.drugbank.com/drugs/DB00206ApprovedWithdrawnIt has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use. … An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Mixtures: Ser-Ap-Es, Ser-AP-ES TabClofedanol
go.drugbank.com/drugs/DB04837ApprovedWithdrawnClofedanol is a centrally-acting cough suppressant available in Canada under the trade name Ulone. It is not available in the United States.
Mixtures: DryMax AF, DryMax AFTirzepatide
go.drugbank.com/drugs/DB15171ApprovedInvestigational[L41820] Later, it was approved under a different brand name ZEPBOUND on November 8, 2023, for the chronic weight management in adults with obesity or overweight with at least one weight-related condition … [A246260] Tirzepatide comprises a 39 amino acid linear synthetic peptide conjugated to a C20 fatty diacid moiety.
Sonrotoclax
go.drugbank.com/drugs/DB18753ApprovedInvestigational[A275521,A275522] On May 13, 2026, the FDA granted accelerated approval to sonrotoclax for the treatment of adult patients with relapsed or refractory mantle cell lymphoma (MCL) after at least two prior … [L56193,A275521] Sonrotoclax was rationally designed as a BH3 mimetic with a shallow and broad interaction with the P2 pocket of BCL-2, achieved through a novel 7-azaspiro[3.5]nonane linker; this binding
Proparacaine
go.drugbank.com/drugs/DB00807ApprovedVet approvedProparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
International brands: Ak-Taine