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Displaying results 921 - 930 of 10000 in total
  1. Drug

    Bortezomib

    go.drugbank.com/drugs/DB00188
    ApprovedInvestigational

    [A204083] The 26S proteasome is a protein complex that degrades ubiquitinated proteins in the ubiquitin-proteasome pathway: reversible inhibition of the 26S proteasome, leading to cell cycle arrest and … [L14180] However, multiple mechanisms may be involved in the anticancer activity of bortezomib.[A204083] Bortezomib was first synthesized in 1995.

    Synonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideProducts: BORTEZOMIB EG, MYBORTE 1.0mg (Bortezomib Powder for Solution for Injection 1.0mg/vial)
  2. Drug

    Zoledronic acid

    go.drugbank.com/drugs/DB00399
    ApprovedInvestigational

    [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994.[A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712]

    Products: ACIDO ZOLEDRONICO SUN PHARMACEUTICAL INDUSTRIES EUROPE BV
  3. Drug

    Ethambutol

    go.drugbank.com/drugs/DB00330
    ApprovedInvestigational

    [A229048] Ethambutol was granted FDA approval on 6 November 1967.[L31663] … [L31743] Ethambutol was first described in the literature in 1961.[A229048] It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_.

    Synonyms: (+)-N,N'-bis(1-(hydroxymethyl)propyl)ethylenediamineProducts: Myambutol Tab 100mg, E-BUTOL TABLET 400 mg
  4. Drug

    Valproate bismuth

    go.drugbank.com/drugs/DB13910
    Approved

    Valproate bismuth is available in Canada in the over-the-counter medication Neo-Laryngobis.

    Products: Neo Laryngobis Enf
  5. Drug

    Prazepam

    go.drugbank.com/drugs/DB01588
    ApprovedIllicit

    Prazepam is a benzodiazepine that is used in the treatment of anxiety disorders. It is a schedule IV drug in the U.S.

    Products: PRAZEPAM EG
  6. Drug

    Sodium citrate

    go.drugbank.com/drugs/DB09154
    ApprovedInvestigational

    It is white, crystalline powder or white, granular crystals, slightly deliquescent in moist air, freely soluble in water, practically insoluble in alcohol. Like citric acid, it has a sour taste. … It works by neutralizing excess acid in the blood and urine. It has been indicated for the treatment of metabolic acidosis.

    Mixtures: Enl, N-ORS Oral Rehydration Salts (Orange Flavour)Categories: Compounds used in a research, industrial, or household setting
  7. Pathway

    Undecoylium chloride iodine complex Drug Metabolism

    smpdb.ca/view/SMP0130610
    Metabolic

    Undecoylium chloride iodine complex passes through the liver and is then excreted from the body mainly through the kidney. … Undecoylium chloride iodine complex is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis.

    Drugs: Undecoylium chloride iodine complex
  8. Drug

    Cefazolin

    go.drugbank.com/drugs/DB01327
    ApprovedInvestigational

    A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

    Synonyms: (6R,7R)-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-7-[(1H-tetrazol-1-ylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acidProducts: Ancef Inj Pws 10gm/vial USP, SEFAMAX IM/IV 1 G ENJ. TOZ İÇEREN FLAKON, 1 ADET
  9. Drug

    Ceftobiprole medocaril

    go.drugbank.com/drugs/DB14733
    Approved

    The EMA's Committee for Medicinal Products for Human Use (CHMP) adopted a negative opinion of ceftobiprole medocaril in February 2010, recommending the refusal of its marketing authorization in the European … [L50467] It received its first approval in Canada in October 2017 for use in certain patients with bacterial pneumonia,[L50472] and was subsequently approved in the United States with additional indications

    Products: Zevtera 500 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  10. Drug

    Dexpanthenol

    go.drugbank.com/drugs/DB09357
    ApprovedInvestigational

    Dexpanthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. … in the epithelium[A32373].

    Mixtures: Supravite 10ml Ampoule, Multivit Et Fer Ampoules Et ComprimesCategories: Vitamin B Complex