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Displaying results 921 - 930 of 6831 in total
  1. Drug

    Mecasermin rinfabate

    go.drugbank.com/drugs/DB14751
    ApprovedInvestigational

    Mecasermin rinfabate manufactured by Insmed Incorporated under the brand name Iplex was approved by the FDA in 2005[L5722]. … The binding of IGF-1 to IGFBP-3 is said to extend the half life and reduce the clearance of IGF-1 in patients with growth hormone resistant syndromes and low levels of IGFBP-3 though this may represent

  2. Indication

    Tick-Borne Encephalitis, European

    go.drugbank.com/conditions/DBCOND0144103
    Drugs: Tick-borne encephalitis vaccine (whole virus, inactivated)
    Synonyms: Encephalitis due to tick-borne encephalitis virus (navigational concept)
  3. Drug

    Phylloquinone

    go.drugbank.com/drugs/DB01022
    ApprovedInvestigational

    [L33319] Phylloquinone has been synthesized since at least 1939,[A234384] and was approved by the FDA prior to 1955.[L33389] … [A234264,A234195,A234259] It is indicated in the treatment of coagulation disorders due to faulty formation of coagulation factors II, VII, IX, and X caused by deficiency or interference in the activity

  4. Drug

    Peppermint oil

    go.drugbank.com/drugs/DB11198
    ApprovedInvestigational

    Due to its effectiveness in relaxing GI smooth muscle but ability to induce gastroesophageal reflux, enteric-coated formulations of peppermint oil has been established which bypass the upper GI tract unmetabolized … Peppermint oil can be applied topically to temporarily relieve tension-type headache.

    Synonyms: Peppermint flowering top oil, Mentha piperita flowering top oilMixtures: Cellzyme ON-TOX, Cellzyme ON-TOX
  5. Drug

    Roflumilast

    go.drugbank.com/drugs/DB01656
    ApprovedInvestigational

    [L46546] It was first approved by the EMA in July 2010, and by the FDA in January 2018.[L37564] Roflumilast topical cream is indicated to treat plaque psoriasis. … to be elucidated.

    Categories: Agents to Treat Airway Disease
  6. Drug

    Rotigotine

    go.drugbank.com/drugs/DB05271
    ApprovedInvestigational

    Rotigotine was developed by Aderis Pharmaceuticals. In 1998 Aderis licensed worldwide development and commercialization rights to Schwarz Pharma of Germany. … It was approved by the European Medicines Agency in 2006 and by the FDA in 2007.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  7. Indication

    Catheter-related Bloodstream Infection

    go.drugbank.com/conditions/DBCOND0037994
    Drugs: Cefazolin · Doripenem · Taurolidine
    Synonyms: Bloodstream infection due to central venous catheter
  8. Drug

    Moxidectin

    go.drugbank.com/drugs/DB11431
    ApprovedInvestigationalVet approved

    Due to these modifications, moxidectin is classified as a second generation macrocyclic lactone. … [A33385] Moxidectin was developed by Medicines Development for Global Health and FDA approved in June 13, 2018.[L2970]

  9. Drug

    Pralidoxime

    go.drugbank.com/drugs/DB00733
    ApprovedInvestigationalVet approved

    Pralidoxime is an antidote to organophosphate pesticides and chemicals. … Organophosphates bind to the esteratic site of acetylcholinesterase, which results initially in reversible inactivation of the enzyme.

  10. Drug

    Potassium chloride

    go.drugbank.com/drugs/DB00761
    ApprovedInvestigationalWithdrawn

    products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release dosage forms and those products formulated for preparation of solution prior to

    Mixtures: GaviLyte - C TM, Gavilyte G TmProducts: POTRELEASE TR TABLET 600MG