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Displaying results 921 - 930 of 10000 in total
  1. Drug

    Acipimox

    go.drugbank.com/drugs/DB09055
    ApprovedInvestigational

    Adverse effects include flushing (associated with Prostaglandin D2), palpitations, and GI disturbances. Flushing can be reduced by taking aspirin 20-30 min before taking Acipimox. … Acipimox inhibits the production of triglycerides by the liver and the secretion of VLDL, which leads indirectly to a modest reduction in LDL and increase in HDL.

    Products: OLBETAM CAPSULE 250 mg
  2. Drug

    Solifenacin

    go.drugbank.com/drugs/DB01591
    ApprovedInvestigational

    [L7511] Solifenacin was granted FDA approval on 19 November 2004.[L7511] … Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.

    Mixtures: VESOMNİ 6 MG/0.4 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADET, Vesomni 6 mg/0,4 mg Tabletten mit veränderter WirkstofffreisetzungCategories: Drugs Used in Benign Prostatic Hypertrophy
  3. Drug

    Trimipramine

    go.drugbank.com/drugs/DB00726
    ApprovedInvestigational

    Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

    Synonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamineProducts: TRIMINEURIN 40 MG/ML Z EIN, TRIMIPRAMIN-NEURAX 100 MG
  4. Drug

    Pasireotide

    go.drugbank.com/drugs/DB06663
    ApprovedInvestigational

    It is marketed as a diaspartate salt called Signifor, which is used in the treatment of Cushing's disease.

    Synonyms: cyclo((4R)-4-(2-aminoethylcarbamoyloxy)-L-prolyl-L-phenylglycyl-D-tryptophyl-L-lysyl-4-O-benzyl-L-tyrosyl-L- phenylalanyl-)Products: SIGNIFOR® LAR 20 MG, SIGNIFOR LAR (20 MG POWDER AND SOLVENT FOR SUSPENSION FOR INJECTION)
  5. Drug

    Adalimumab

    go.drugbank.com/drugs/DB00051
    ApprovedInvestigational

    [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA.[A39983] This drug is frequently known as _Humira_. … [L4799] Other biosimilars include adalimumab-fkjp - which was approved in July 2022 -,[L42495] adalimumab-bwwd - which was approved in August 2022 -,[L42935], adalimumab-aacf - which was approved in October

    International brands: Humira PenProducts: AMGEVITA 20 mg/0.4 ml solution for injection in pre-filled syringe, AMGEVITA SOLUTION FOR INJECTION IN PREFILLED SYRINGE 20 mg/0.4 ml
  6. Drug

    Clomipramine

    go.drugbank.com/drugs/DB01242
    ApprovedInvestigationalVet approved

    The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. … They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, clomipramine does not affect mood or arousal, but may cause sedation.

    Synonyms: 3-(3-chloro-5H-dibenzo[b,F]azepin-5-yl)-N,N-dimethylpropan-1-amine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamineProducts: ANAFRANIL SR 75 MG UZATILMIŞ SALIMLI BÖLÜNEBİLİR TABLET, 20 ADET, ANAFRANIL® RETARD 75 MG TABLETAS RECUBIERTAS DE LIBERACION PROLONGADA
  7. Drug

    Nimodipine

    go.drugbank.com/drugs/DB00393
    ApprovedInvestigational

    It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. … Compared to other calcium channel blocking agents, nimodipine exhibits greater effects on cerebral circulation than on peripheral circulation.

    Synonyms: isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylateProducts: NIMODIPINA EG, NITODAL
  8. Drug

    Nabumetone

    go.drugbank.com/drugs/DB00461
    Approved

    [A179077] While slightly reduced, possibly due to a degree of cyclooxygenase-2 selectivity (COX-2), nabumetone still produces significant adverse effects in the GI tract. … Nabumetone was developed by Smithkline Beecham under the trade name Relafen and first received FDA approval in December, 1991.[L6568]

    Mixtures: NuDroxiPAK N-500Products: Relafen DS, Nabumetone 500 mg
  9. Drug

    Zofenopril

    go.drugbank.com/drugs/DB13166
    ApprovedInvestigational

    It is an angiotensin-converting enzyme (ACE) inhibitor.

    Mixtures: ZOFENOPRIL E IDROCLOROTIAZIDE EG, Zofenil plus 30 mg/12,5 mg FilmtablettenCategories: Agents Acting on the Renin-Angiotensin System
  10. Drug

    Nifuroxazide

    go.drugbank.com/drugs/DB13855
    Investigational

    Mixtures: METRONIDAZOL/NIFUROXAZIDA 300 MG/100 MG., METARSAL N CAPSULASProducts: GASTIL 200 MG, NIRABEN CAPSULE 200 mg