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Daptomycin
go.drugbank.com/drugs/DB00080ApprovedInvestigational[A231379, A231384, L32534] Chemically, daptomycin comprises 13 amino acids, including several non-standard and D-amino acids, with the C-terminal 10 amino acids forming an ester-linked ring and the N-terminal … [A231384] Early work on developing daptomycin was abandoned due to observed myopathy but was resumed in 1997 when Cubist Pharmaceuticals Inc. licensed daptomycin; it was found that a once-daily dosing
Products: DATABIN® 500 MG, DAPTOMRED 500 MG/ VIALRaltegravir
go.drugbank.com/drugs/DB06817ApprovedInvestigationalRaltegravir is an antiretroviral drug produced by Merck & Co., used to treat HIV infection. It received approval by the U.S. Food and Drug Administration (FDA) on 12 October 2007, the first of a new class of HIV drugs, the integrase ...
Products: Chewable Tablet 100 mg, ISENTRESS 400 MG FILM KAPLI TABLET, 60 ADETBCG vaccine
go.drugbank.com/drugs/DB12768ApprovedInvestigationalWithdrawnBCG vaccine has been investigated for the treatment of Neoplasms, Bladder Cancer, Neoplasms by Site, Urologic Diseases, and Urologic Neoplasms, among others.
Products: CALGEVAX-BCG 11.25 MG INTRAVEZIKAL ENJEKSIYON IÇIN LIYOFILIZE TOZ IÇEREN AMPUL, 10 ADET, SII-BCG 1 ML ID ENJEKSIYONLUK SUSPANSIYON ICIN LIYOFILIZE TOZ ICEREN COK DOZLU FLAKON, 10 ADETPilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigationalA naturally occurring alkaloid derived from the Pilocarpus plants, pilocarpine is a muscarinic acetylcholine agonist. Pilocarpine is associated with parasympathomimetic effects by selectively working on muscarinic receptors. Pilocarpine ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsSynonyms: 2(3H)-FURANONE, 3-ETHYLDIHYDRO-4-((1-METHYL-1H-IMIDAZOL-5-YL)METHYL)-, (3S-CIS)-Cimetidine
go.drugbank.com/drugs/DB00501ApprovedInvestigationalIt also blocks the activity of cytochrome P-450 which might explain proposals for use in neoadjuvant therapy. … Cimetidine has a range of pharmacological actions. It inhibits gastric acid secretion, as well as pepsin and gastrins output.
Synonyms: 1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidineInternational brands: Tagamet HB 200Ivabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigational≥70 beats per minute, who are not on beta-blockers due to contraindications or already receiving maximum beta-blocker dose. … Therefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing
Mixtures: Implicor 50 mg/5 mg Filmtabletten, IMPLICOR FILM-COATED TABLET 50 mg/5 mgCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEptifibatide
go.drugbank.com/drugs/DB00063ApprovedInvestigationalSynthetic cyclic hexapeptide that binds to platelet receptor glycoprotein and inhibits platelet aggregation. Derived from venom of the Southeastern pygmy rattlesnake (Sistrurus miliarus barbouri), eptifibatide is a cyclic heptapeptide th...
Products: EPTICARD 20 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, INTEGRILIN INYECTABLE 2 MG/ML.Clobetasol propionate
go.drugbank.com/drugs/DB01013ApprovedInvestigational[L11815] It has demonstrated superior activity compared to [fluocinonide][A190963] and was first described in the literature in 1974. … [A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809]
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 SubstratesProducts: CLONOVATE CREAM 0.05 g/100 g, Clobex 500 Mikrogramm/g ShampooSomapacitan
go.drugbank.com/drugs/DB15093ApprovedInvestigational[A219146] Somapacitan was granted FDA approval on 28 August 2020.[L15666] … Somapacitan, also known as NNC0195-0092,[A219136] is a growth hormone analog indicated to treat adults with growth hormone deficiency.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Sogroya® 10 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet), Sogroya® 5 mg/1.5 mL Enjeksiyonluk Çözelti İçeren Kullanıma Hazır Kalem (1 adet)Lercanidipine
go.drugbank.com/drugs/DB00528ApprovedInvestigationalWithdrawnLercanidipine is a calcium channel blocker of the dihydropyridine class. It is sold under various commercial names including Zanidip.
Mixtures: ZANIPRESS 10 MG/10 MG FILM TABLET, 30 ADET, ZANIPRESS 10 MG/10 MG FILM TABLET, 90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors