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Displaying results 921 - 930 of 10000 in total
  1. Target

    Acyl-coenzyme A thioesterase 2, mitochondrial

    go.drugbank.com/bio_entities/BE0013225
    EnzymeHumans

    Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels (PubMed:10944470, PubMed:16940157).

    Polypeptides: Acyl-coenzyme A thioesterase 2, mitochondrialSynonyms: Acyl-coenzyme A thioester hydrolase 2a
  2. Drug

    Insulin glulisine

    go.drugbank.com/drugs/DB01309
    Approved

    Insulin glulisine is a biosynthetic, rapid-acting human insulin analogue produced in a non-pathogenic laboratory strain of _Escherichia coli_ (K12). … As a result, people with T1D rely primarily on exogenous forms of insulin, such as insulin glulisine, to lower glucose levels in the blood.

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme InducersProducts: Apidra SoloStar 100 Units/ml Solution for injection in a pre-filled pen, APIDRA SOLOSTAR 100 UNITS/ML, SOLUTION FOR INJECTION IN A PRE-FILLED PEN
  3. Drug

    Cinnamon oil

    go.drugbank.com/drugs/DB15986
    ApprovedInvestigational

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsProducts: Nwk A-FV
  4. Drug

    Anistreplase

    go.drugbank.com/drugs/DB00029
    ApprovedWithdrawn

    A p-anisoyl group is chemically conjugated to a complex of bacterial-derived streptokinase and human Plasma-derived Lys-plasminogen proteins. … Eminase is a lyophilized (freeze-dried) formulation of anistreplase, the p-anisoyl derivative of the primary Lys-plasminogen-streptokinase activator complex (a complex of Lys-plasminogen and streptokinase

    Synonyms: Anisoylated plasminogen streptokinase activator complex
  5. Target

    L-lactate dehydrogenase A-like 6B

    go.drugbank.com/bio_entities/BE0000100
    TargetHumans

    Catalyzes the interconversion of L-lactate and pyruvate with nicotinamide adenine dinucleotide NAD(+) as a coenzyme

    Polypeptides: L-lactate dehydrogenase A-like 6B
  6. Target

    Serine/threonine-protein kinase A-Raf

    go.drugbank.com/bio_entities/BE0000434
    TargetHumans

    Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. Phosphorylates PFKFB2 (PubMed:36402789)

    Polypeptides: Serine/threonine-protein kinase A-RafSynonyms: Proto-oncogene A-Raf, Proto-oncogene A-Raf-1
  7. Target

    Coenzyme A biosynthesis bifunctional protein CoaBC

    go.drugbank.com/bio_entities/BE0002020
    TargetEscherichia coli (strain K12)

    Catalyzes two sequential steps in the biosynthesis of coenzyme A.

    Polypeptides: Coenzyme A biosynthesis bifunctional protein CoaBC
  8. Target

    Chain A, Red Copper Protein Nitrosocyanin

    go.drugbank.com/bio_entities/BE0002711
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Chain A, Red Copper Protein Nitrosocyanin
  9. Target

    Peptidyl-prolyl cis-trans isomerase A

    go.drugbank.com/bio_entities/BE0004194
    TargetEscherichia coli (strain K12)

    PPIases accelerate the folding of proteins (Probable). It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (PubMed:2190212).

    Polypeptides: Peptidyl-prolyl cis-trans isomerase ASynonyms: PPIase A, Rotamase A
  10. Target

    Platelet-derived growth factor subunit A

    go.drugbank.com/bio_entities/BE0010246
    TargetHumans

    Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum ...

    Polypeptides: Platelet-derived growth factor subunit ASynonyms: PDGF subunit A, Platelet-derived growth factor A chain