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Vinorelbine
go.drugbank.com/drugs/DB00361ApprovedInvestigationalIt was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].
Categories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: RENOVEL 10 MG/1 ML IV ENJEKSİYONLUK ÇÖZELTİ İÇEREN FLAKON, 1 ADET, VINALINE 50 MG/5 ML IV İNFÜZYON İÇİN KONSANTRE ÇÖZELTİ İÇEREN FLAKON, 1 ADETMiconazole
go.drugbank.com/drugs/DB01110ApprovedInvestigationalVet approved[A203636, A203639] Miconazole was first synthesized in 1969 and first granted FDA approval on January 8, 1974, for sale by INSIGHT Pharmaceuticals as a topical cream. … [A214523, L14021] It is currently available as a variety of prescription and over the counter products.
International brands: Daktarin IV, Monistat IVMixtures: Monistat 3 Combination Pack 3-Day in Pre-Filled Applicators, Monistat 3 Combination Pack 3-Day in Pre-Filled ApplicatorsSunflower oil
go.drugbank.com/drugs/DB14329InvestigationalSunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: OrgaPlus Super Care Balm for combination and oi ly skin type 20g, OrgaPlus Super Care Balm for combination and oi ly skin type 14gAmbroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalAmbroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. … role in the body’s natural defence mechanisms.
Mixtures: MATIS-ASynonyms: N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol, N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanolPirfenidone
go.drugbank.com/drugs/DB04951ApprovedInvestigationalPirfenidone is a synthetic pyridone drug. … [A251370] It is an antifibrotic agent with anti-inflammatory and antioxidant properties [A251370] that is used to treat idiopathic pulmonary fibrosis (IPF),[L26801] which is a chronic, progressive form
Products: KITOSCELL LPGlycopyrronium
go.drugbank.com/drugs/DB00986ApprovedInvestigationalVet approved[L33105] Glycopyrronium is commonly prescribed as a first line treatment for a wide variety indications and is considered to have a wider therapeutic window than [tiotropium]. … [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.
Synonyms: Glycopyrrolate ion, Glycopyrronium ionProducts: Robinul 0.2mg/ml Liq InjOmeprazole
go.drugbank.com/drugs/DB00338ApprovedInvestigationalVet approvedOriginally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders. … Omeprazole is generally effective and well-tolerated, promoting its popular use in children and adults [FDA label].
Mixtures: MOVIDOL PROTECProducts: PROTEC, PRAZIDEC - IHypotension
go.drugbank.com/conditions/DBCOND0020133Synonyms: Fall in blood pressure, Drop in blood pressureMonepantel
go.drugbank.com/drugs/DB18755InvestigationalSynonyms: N-(2-cyano-1-((2s)-5-cyano-2-(trifluoromethyl)phenoxy)propan-2-yl)-4-(trifluoromethylsulfanyl)benzamide, Benzamide, n-((1s)-1-cyano-2-(5-cyano-2-(trifluoromethyl)phenoxy)-1-methylethyl)-4-((trifluoromethyl)thio)-Cognitive Function Abnormal
go.drugbank.com/conditions/DBCOND0089677Synonyms: Disturbance in cognition