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Tranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalTranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. … An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineBemiparin
go.drugbank.com/drugs/DB09258ApprovedInvestigationalWithdrawnLike semuloparin, bemiparin is classified as an ultra-LMH because of its low mean molecular mass of 3600 daltons, which is a unique property of this class [A7866]. … Bemiparin is an antithrombotic and belongs to the group of drugs known as the low molecular weight heparins (LMWH).
Products: HIBOR 2500 IU/0,2 ML KULLANIMA HAZIR 2 ENJEKTOR, HIBOR 5000 IU/0,2 ML SC KULLANIMA HAZIR ENJEKTÖR, 2 ADETAsciminib
go.drugbank.com/drugs/DB12597ApprovedInvestigational[L38995,A241055] Asciminib received FDA approval on October 29, 2021 (Scemblix, Novartis AG).[L39000] … More specifically, it is an inhibitor of the ABL1 kinase activity of the BCR-ABL1 fusion protein[L38995] which serves as a driver of CML proliferation in most patients with the disease.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesProducts: AZEVAY 20 MG FİLM KAPLI TABLET , 60 ADET, AZEVAY 40 MG FİLM KAPLI TABLET , 60 ADETPropranolol
go.drugbank.com/drugs/DB00571ApprovedInvestigationalPropranolol is a racemic mixture of 2 enantiomers where the S(-)-enantiomer has approximately 100 times the binding affinity for beta adrenergic receptors. … [L6904] Propranolol is used to treat a number of conditions but most commonly is used for hypertension.[L6901,L6904,L6907] Propranolol was granted FDA approval on 13 November 1967.[L6904]
Synonyms: 1-(isopropylamino)-3-(1-naphthyloxy)propan-2-ol, 1-((1-Methylethyl)amino)-3-(1-naphthalenyloxy)-2-propanolMixtures: ARTENSOL® H 40 MG TABLETASConestat alfa
go.drugbank.com/drugs/DB09228ApprovedC1 Esterase Inhibitor (Recombinant) is a recombinant analogue of endogenous complement component-1 esterase inhibitor (rhC1INH), purified from the milk of transgenic rabbits. … Additionally, C4 and C2 cleavage occurs resulting in auto-activation of the complement system.
Categories: Drugs Used in Hereditary AngioedemaProducts: RUCONEST 2100 U IV ENJEKSİYONLUK ÇÖZELTİ İÇİN TOZ İÇEREN FLAKON, 1 ADET, Pulver und Lösungsmittel zur Herstellung einer InjektionslösungMelatonin
go.drugbank.com/drugs/DB01065ApprovedInvestigationalNutraceuticalVet approvedMelatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. … Reduced melatonin production has also been proposed as a likely factor in the significantly higher cancer rates in night workers.
Synonyms: N-[2-(5-methoxyindol-3-yl)ethyl]acetamide, 5-methoxy-N-acetyl tryptamineInternational brands: Mela-TLacidipine
go.drugbank.com/drugs/DB09236ApprovedIn randomised, well-controlled trials, administration of daily single-dose lacidipine ranging from 2-6 mg demonstrated comparable antihypertensive efficacy similar to that of other long-acting dihydropyridine … It is available as once-daily oral tablets containing 2 or 4 mg of the active compound commonly marketed as Lacipil or Motens. It is not currently FDA-approved.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: LACIPIL 4 MG FILM KAPLI TABLET, 28 ADET, LACIPIL TABLET 4 mgMebendazole
go.drugbank.com/drugs/DB00643ApprovedInvestigationalVet approvedA benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules. [PubChem]
Mixtures: L-OMBRIX-DUET, L-OMBRIX-DUETCategories: Heterocyclic Compounds, 2-RingRifampin
go.drugbank.com/drugs/DB01045ApprovedInvestigationalRifampin, also known as rifampicin, is a broad-spectrum antimicrobial [A263748] that was first discovered in 1965 [A263753] and clinically used in 1968.
Mixtures: RIFAMPICIN 75 MG / ISONIAZID 50 MG (FDC 2 ANAK), RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGCategories: P-glycoprotein inducers, Cytochrome P-450 CYP1A2 InducersCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigational[A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment multiple sclerosis.[A263718] … [A350] Cladribine was first approved in the United States in 1993 [A263713] initially as a treatment for a number of hematological malignancies; currently, it is approved for the treatment of hairy cell
Categories: 2-Chloroadenosine, Heterocyclic Compounds, 2-RingSynonyms: (2R,3S,5R)-5-(6-amino-2-chloropurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol, 2-Chloro-2'-deoxyadenosine