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Ondansetron
go.drugbank.com/drugs/DB00904ApprovedInvestigationalWithdrawn[L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation. … It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
Categories: Serotonin 5-HT3 Receptor Antagonists, Antiemetic Serotonin 5-HT3 Receptor AntagonistsProducts: ONDANSETRON EG, ONZYD 4 MG AGIZDA DAGILAN 10 TABLETSebelipase alfa
go.drugbank.com/drugs/DB11563ApprovedInvestigationalIt was first approved by both the FDA and EMA in 2015 and is marketed under the brand name Kanuma (Alexion Pharmaceuticals).[L39337,L39342] … This lipid accumulation can lead to end-organ damage in the form of liver dysfunction or malabsorption secondary to intestinal dysfunction.
Synonyms: SBC-102Products: KANUMA® 2 MG/ML CONCENTRADO PARA SOLUCION PARA INFUSION.Epinastine
go.drugbank.com/drugs/DB00751ApprovedIt has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2A Receptor AntagonistsProducts: FLURINOL COMPRIMIDOS RECUBIERTOS 10 MG., FLURINOL ® JARABE 0.2 G / 100 MLEtravirine
go.drugbank.com/drugs/DB06414ApprovedInvestigationalOn March 26, 2012, approval was extended for use in treatment-experienced pediatric patients 6 to 18 years of age, weighing at least 16 kg. … In 2013, reports of Autoimmune disorders (such as Graves’ disease, polymyositis, and Guillain-Barré syndrome) in the setting of immune reconstitution, as well as more in depth information about the development
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersProducts: INTELENCE 100 MG TABLETS, INTELENCE 100 MG TABLET, 120 ADETSolifenacin
go.drugbank.com/drugs/DB01591ApprovedInvestigational[L7511] It has a long duration of action as it is usually taken once daily.[L7511] Solifenacin was granted FDA approval on 19 November 2004.[L7511] … Solifenacin is a competitive muscarinic receptor antagonist indicated to treat an overactive bladder with urinary incontinence, urgency, and frequency.
Mixtures: VESOMNİ 6 MG/0.4 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 ADET, Vesomni 6 mg/0,4 mg Tabletten mit veränderter WirkstofffreisetzungCategories: Heterocyclic Compounds, 2-Ring, Drugs Used in Benign Prostatic HypertrophyDiazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigational[A255647,L44612] It is chemically related to thiazide diuretics but does not inhibit carbonic anhydrase and does not have chloriuretic or natriuretic activity. … [A255647,L44612] In March 2025, an extended-release formulation of diazoxide choline was approved by the FDA for the treatment of hyperphagia in patients with Prader-Willi syndrome, becoming the first
Synonyms: 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxideCategories: Heterocyclic Compounds, 2-Ring, Arteriolar Smooth Muscle, Agents Acting OnTocilizumab
go.drugbank.com/drugs/DB06273ApprovedInvestigational[L12789] It was later approved by Health Canada on 30 April 2010. … [L12789] It was first described in the literature in 2003 when Chugai, a subsidiary of Roche began developing IL-6 inhibiting monoclonal antibodies.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersProducts: ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 4 ADET, ACTEMRA 200 MG/10 ML IV INFUZYONLUK COZELTI KONSANTRESI İÇEREN FLAKON, 1 ADETFoscarnet
go.drugbank.com/drugs/DB00529ApprovedInvestigationalAn antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpes viruses and HIV.
Products: FOSCAVIR INFUSION 24 mg/ml, Foscarnet Tillomed 24 mg/ml InfusionslösungArmodafinil
go.drugbank.com/drugs/DB06413ApprovedInvestigationalFood and Drug Administration (FDA) in June 2007. … Research has shown that armodafinil significantly improves driving simulator performance in patients with SWD. Armodafinil consists of the (−)-R-enantiomer of the racemic modafinil.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2B6 InducersSynonyms: (–)-2-[(R)-(diphenylmethyl)sulfinyl]acetamideLoperamide
go.drugbank.com/drugs/DB00836ApprovedInvestigational[A251610] It is a highly lipophilic synthetic phenylpiperidine opioid that works by binding to mu-opioid receptors on intestinal muscles to decrease intestinal motility and electrolyte loss. … [A251610] Loperamide has a chemical structure that is similar to diphenoxylate and haloperidol;[A6249] however, loperamide works on mu (μ)-opioid receptors to mediate its pharmacological actions.
Mixtures: Dg Health Anti Diarrheal Anti Gas, Meds on the GoCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates