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Displaying results 931 - 940 of 2454 in total
  1. Drug

    Befotertinib

    go.drugbank.com/drugs/DB18844
    Investigational

    Befotertinib is under investigation in clinical trial NCT05007938 (Befotertinib and Icotinib in Treatment-naive Patients With Advanced Egfr-mutant Lung Cancer).

    Categories: P-glycoprotein inhibitors
  2. Drug

    Avenciguat

    go.drugbank.com/drugs/DB18882
    Investigational

    Avenciguat is under investigation in clinical trial NCT05282121 (A Study to Test Whether BI 685509 Alone or in Combination With Empagliflozin Helps People With Liver Cirrhosis Caused by Viral Hepatitis or Non-alcoholic Steatohepatitis (N...

    Categories: P-glycoprotein substrates
  3. Drug

    Epaminurad

    go.drugbank.com/drugs/DB18973
    Investigational

    Epaminurad is under investigation in clinical trial NCT05815901 (A Therapeutic Confirmatory Study of Epaminurad Versus Febuxostat in Gout Patients).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Substrates
  4. Drug

    Bersacapavir

    go.drugbank.com/drugs/DB19035
    Investigational

    Bersacapavir is under investigation in clinical trial NCT03365947 (Study of ARO-HBV in Normal Adult Volunteers and Patients With Hepatitis B Virus (HBV)).

    Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Substrates
  5. Drug

    p-Boronophenylalanine

    go.drugbank.com/drugs/DB19158
    Investigational

    p-Boronophenylalanine is under investigation in clinical trial NCT00039572 (Boron Neutron Capture Therapy in Treating Patients With Glioblastoma Multiforme or Melanoma Metastatic to the Brain).

    Synonyms: L-p-boronophenylalanine
  6. Drug

    Human placenta hydrolysate

    go.drugbank.com/drugs/DB19297
    Investigational

    Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 Enzyme Inhibitors
  7. Drug

    BPR-0L075

    go.drugbank.com/drugs/DB17155
    Investigational

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  8. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA top...

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 Inhibitors
  9. Drug

    Ceftriaxone

    go.drugbank.com/drugs/DB01212
    ApprovedInvestigational

    Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic. It has a very long half-life compared to other cephalosporins and is high penetrable into the meninges , eyes , and inner ear . Ceftriaxone has broader and strong...

    Categories: P-glycoprotein inhibitorsProducts: CEFTRIAXONE SIGMA TAU GENERICS, CEFTRIAXONE DOC GENERICI
  10. Drug

    Estazolam

    go.drugbank.com/drugs/DB01215
    ApprovedIllicitInvestigational

    A benzodiazepine with anticonvulsant, hypnotic, and muscle relaxant properties. It has been shown in some cases to be more potent than diazepam or nitrazepam.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates