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Displaying results 9431 - 9440 of 10000 in total
  1. Drug

    Tolinapant

    go.drugbank.com/drugs/DB16160
    Investigational

    ASTX660 is under investigation in clinical trial NCT02503423 (Phase 1-2 Study of ASTX660 in Subjects With Advanced Solid Tumors and Lymphomas).

  2. Drug

    Obefazimod

    go.drugbank.com/drugs/DB14828
    Investigational

    ABX-464 is under investigation in clinical trial NCT03905109 (Safety Evaluation of ABX464 in Patients With Moderate to Severe Active Crohn's Disease).

  3. Drug

    TS-104

    go.drugbank.com/drugs/DB33943
    Experimental

    in Subjects With Select Advanced Solid Tumors). … TS-104 is under investigation in clinical trial NCT07814248 (A Phase 1, First-in-Human (FIH), Open-Label, Dose-Escalation and Dose Expansion Study of the Peptide Drug Conjugate (PDC), TS-104, as a Monotherapy

  4. Drug

    AS-8112

    go.drugbank.com/drugs/DB09207
    Experimental

    It has been shown to exert potent antiemetic effects in animal studies and has been investigated for potential medical use. … AS-8112 is a synthetic compound that acts as a selective antagonist at the dopamine receptor subtypes D2 and D3, and the serotonin receptor 5-HT3.

  5. Drug

    Tarextumab

    go.drugbank.com/drugs/DB12104
    Investigational

    Tarextumab has been used in trials studying the treatment of Solid Tumors, Stage IV Pancreatic Cancer, and Stage IV Small Cell Lung Cancer.

  6. Drug

    2-Hydroxyestradiol

    go.drugbank.com/drugs/DB07706
    Experimental

    2-Hydroxyestradiol is classified as an endogenous steroid, catechol estrogen, and metabolite of estradiol. It is also a positional isomer of estriol. [A31630]

  7. Drug

    Pateclizumab

    go.drugbank.com/drugs/DB14997
    Investigational

    With Adalimumab in Combination With a DMARD in Patients With Active Rheumatoid Arthritis). … Pateclizumab is under investigation in clinical trial NCT01225393 (A Study to Evaluate the Efficacy and Safety of MLTA3698A in Combination With a Disease-Modifying Anti-Rheumatic Drug (DMARD) Compared

  8. Drug

    CDX-1135

    go.drugbank.com/drugs/DB17607
    Investigational

    It was investigated in clinical trials for post-cardiopulmonary bypass syndrome and kidney damage. … CDX-1135, formerly TP-10, is a soluble, recombinant human Complement Receptor Type 1 (sCR1) developed by Avant Immunotherapeutics (now Celldex).

  9. Drug

    LV-SMENP Vaccine

    go.drugbank.com/drugs/DB15804
    Experimental

    This vaccine is also administered with antigen-specific cytotoxic T lymphocytes (CTLs). As of August 2020, this vaccine is being tested for prophylaxis against COVID-19 in human clinical trials. … are based on domains of selected viral proteins.

  10. Drug

    GZ-389988

    go.drugbank.com/drugs/DB16056
    Investigational

    GZ-389988 is under investigation in clinical trial NCT02845271 (Proof-of-concept Study to Assess the Efficacy, Tolerability and Safety of a Single Intraarticular Dose of GZ389988 Versus Placebo in Patients