Search
Prostaglandin E2 receptor EP1 subtype
go.drugbank.com/bio_entities/BE0000064TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system.
Polypeptides: Prostaglandin E2 receptor EP1 subtypeSynonyms: PGE receptor EP1 subtype, Prostanoid EP1 receptorRetinoic acid receptor RXR-beta
go.drugbank.com/bio_entities/BE0000078TargetHumansReceptor for retinoic acid.
Polypeptides: Retinoic acid receptor RXR-betaSynonyms: Retinoid X receptor beta, Nuclear receptor subfamily 2 group B member 2Glutamate receptor ionotropic, kainate 1
go.drugbank.com/bio_entities/BE0000346TargetHumansThe receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist … Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid.
Polypeptides: Glutamate receptor ionotropic, kainate 1Synonyms: Glutamate receptor 5, Excitatory amino acid receptor 3Prostaglandin E2 receptor EP2 subtype
go.drugbank.com/bio_entities/BE0000368TargetHumansReceptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. … The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle
Polypeptides: Prostaglandin E2 receptor EP2 subtypeSynonyms: PGE receptor EP2 subtype, Prostanoid EP2 receptorRetinoic acid receptor RXR-alpha
go.drugbank.com/bio_entities/BE0000412TargetHumansReceptor for retinoic acid that acts as a transcription factor (PubMed:10874028, PubMed:11162439, PubMed:11915042, PubMed:37478846).
Polypeptides: Retinoic acid receptor RXR-alphaSynonyms: Retinoid X receptor alpha, Nuclear receptor subfamily 2 group B member 1Interleukin-11 receptor subunit alpha
go.drugbank.com/bio_entities/BE0000416TargetHumansReceptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission.
Polypeptides: Interleukin-11 receptor subunit alphaSynonyms: IL-11 receptor subunit alphaGlutamate receptor ionotropic, NMDA 2B
go.drugbank.com/bio_entities/BE0000417TargetHumansIts phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity)
Polypeptides: Glutamate receptor ionotropic, NMDA 2BSynonyms: N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3Glycine receptor subunit alpha-1
go.drugbank.com/bio_entities/BE0000433TargetHumansSubunit of heteromeric glycine-gated chloride channels (PubMed:14551753, PubMed:23994010, PubMed:25730860, PubMed:37821459). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contri...
Polypeptides: Glycine receptor subunit alpha-1Synonyms: Glycine receptor 48 kDa subunit, Glycine receptor strychnine-binding subunitGlutamate receptor ionotropic, NMDA 3B
go.drugbank.com/bio_entities/BE0000534TargetHumansForms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits. … GluN3B subunit also binds D-serine and, in the absence of glycine, activates glycinergic receptor complexes, but with lower efficacy than glycine (By similarity).
Polypeptides: Glutamate receptor ionotropic, NMDA 3BSynonyms: N-methyl-D-aspartate receptor subtype 3BInterleukin-2 receptor subunit alpha
go.drugbank.com/bio_entities/BE0000658TargetHumansReceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity.
Polypeptides: Interleukin-2 receptor subunit alphaSynonyms: IL-2 receptor subunit alpha