Search
Atogepant
go.drugbank.com/drugs/DB16098ApprovedInvestigational[A239094] The "gepants" family of drugs, including atogepant, are comparatively well-tolerated[A189207,L38739] and may provide a desirable treatment option for patients struggling with adverse reactions … [valproic acid] or [topiramate]) or beta-blockers (e.g. [propranolol]), all of which can be associated with significant adverse effects.
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: AQUIPTA® 10 MG, AQUIPTA® 60 MGSodium channel protein type 10 subunit alpha
go.drugbank.com/bio_entities/BE0000177TargetHumansTetrodotoxin-resistant channel that mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sod...
Polypeptides: Sodium channel protein type 10 subunit alphaATP-sensitive inward rectifier potassium channel 10
go.drugbank.com/bio_entities/BE0009591TargetHumansMay be responsible for potassium buffering action of glial cells in the brain (By similarity). Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it (Pu...
Polypeptides: ATP-sensitive inward rectifier potassium channel 10Synonyms: Potassium channel, inwardly rectifying subfamily J member 10Ergoloid mesylate
go.drugbank.com/drugs/DB01049ApprovedErgoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...
Mixtures: TOTERJİN DAMLA, 50 CCCategories: Heterocyclic Compounds with 4 or More RingsMitogen-activated protein kinase kinase kinase 10
go.drugbank.com/bio_entities/BE0009462TargetHumansActivates the JUN N-terminal pathway
Polypeptides: Mitogen-activated protein kinase kinase kinase 10Tumor necrosis factor ligand superfamily member 10
go.drugbank.com/bio_entities/BE0010497TargetHumansCytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG (PubMed:10549288, PubMed:26457518). Induces apoptosis. Its activity may be modulated by binding to the d...
Polypeptides: Tumor necrosis factor ligand superfamily member 10Apremilast
go.drugbank.com/drugs/DB05676ApprovedInvestigational[L7501] In July 2019, apremilast was granted a new FDA approval for the treatment of oral ulcers associated with Behcet's disease, an autoimmune condition that causes recurrent skin, blood vessel, and … Apremilast, also known as Otezla, is a phosphodiesterase 4 (PDE4) inhibitor used to treat various types of symptoms resulting from certain inflammatory autoimmune diseases.
Mixtures: OTEZLA (10 MG 20 MG 30 MG), OTEZLA (10 MG 20 MG 30 MG)Categories: Heterocyclic Compounds, 1-RingFerrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Mixtures: Vitamin C 202,8 mg/0,8 mg/100 mg - Hartkapseln, IROZINC ŞURUP ,100 MLProducts: FERAMAT 100 MG KAPSUL, 100 ADET, FERAMAT 100 MG KAPSUL, 30 ADETMinoxidil
go.drugbank.com/drugs/DB00350ApprovedInvestigationalA potent direct-acting peripheral vasodilator (vasodilator agents) that reduces peripheral resistance and produces a fall in blood pressure.
Categories: Heterocyclic Compounds, 1-Ring, Antihypertensive Agents Indicated for HypertensionSynonyms: 6-Piperidin-1-ylpyrimidine-2,4-diamine 3-oxideAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigationalAbiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis … [L54773,L54768] As abiraterone has poor oral bioavailability and is susceptible to hydrolysis by esterases, abiraterone acetate was developed as an orally bioavailable prodrug with enhanced stability
Synonyms: 17-(3-Pyridyl)androsta-5,16-dien-3beta-ol, (3β)-17-(pyridin-3-yl)androsta-5,16-dien-3-olProducts: Abirateron 1A Pharma 500 mg - Filmtabletten, Abirateron 1A Pharma 1000 mg – Filmtabletten