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Metiamide H2 Anti-Histamine Action Pathway
smpdb.ca/view/SMP0123167Drug actionMetiamide is an histamine H2 receptor antagonist used to treat stomach ulcers and Gastroesophageal Reflux Disease (GERD). After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stomach epithe...
Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · MetiamideEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortRoxatidine Acetate H2 Anti-Histamine Action Pathway
smpdb.ca/view/SMP0123168Drug actionRoxatidine Acetate is an histamine H2 receptor antagonist used to treat stomach ulcers and Gastroesophageal Reflux Disease (GERD). After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stoma...
Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · Roxatidine acetateEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortNizatidine H2 Anti-Histamine Action Pathway
smpdb.ca/view/SMP0126776Drug actionNizatidine is an H2 Histamine receptor antagonist used to treat acid reflux disorders and a variety of ulcers. Nizatidine is taken orally as a solution or a capsule. Once it is transported to gastric basolateral membrane of parietal cell...
Drugs: ATP · Nizatidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphateEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortLavoltidine H2 Anti-histamine Action Pathway
smpdb.ca/view/SMP0126790Drug actionLavoltidine has been used in trials studying the diagnostic of Reflux, Gastroesophageal and Gastroesophageal Reflux Disease. After being taken orally, it is absorbed in the GI tract and travels through the blood to get to the stomach epi...
Drugs: ATP · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphate · LavoltidineEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortMetharbital
go.drugbank.com/drugs/DB00463ApprovedWithdrawnMetharbital is a barbiturate anticonvulsant, similar to phenobarbital, marketed as Gemonil by Abbott Laboratories. It was patented in 1905 by Emil Fischer of Merck.
Categories: Heterocyclic Compounds, 1-RingFamotidine H2 Anti-Histamine Action Pathway
smpdb.ca/view/SMP0126789Drug actionFamotidine is a histamine H2 receptor antagonist used to treat gastroesophageal reflux disease and various ulcers. Famotidine displays high selectivity towards H2 histamine receptors compared to other H2 anti-histamines. After being take...
Drugs: ATP · Famotidine · Potassium cation · Magnesium cation · Zinc · Cyclic adenosine monophosphateEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortApraclonidine
go.drugbank.com/drugs/DB00964ApprovedInvestigationalApraclonidine, also known as iopidine, is a sympathomimetic used in glaucoma therapy. It is an alpha2-adrenergic agonist.
Synonyms: 4-AminoclonidineCategories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-1 Receptor AgonistsButobarbital
go.drugbank.com/drugs/DB01353ApprovedIllicitButobarbital is a sedative and a hypnotic drug.
Categories: Heterocyclic Compounds, 1-RingOxantel
go.drugbank.com/drugs/DB13670InvestigationalOxantel is an anthelmintic drug that targets parasitic acetylcholine receptors.[A275093, A275098]
Mixtures: VANPAR®, PIRAXTEL® SUSPENSIONCategories: Heterocyclic Compounds, 1-RingMuscular Gi Protein Cascade
smpdb.ca/view/SMP0126972PhysiologicalG proteins, also known as guanine nucleotide-binding proteins, are a family of proteins that act as molecular switches inside cells, and are involved in transmitting signals from a variety of stimuli outside a cell to its interior. Their...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1