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Displaying results 9551 - 9560 of 10000 in total
  1. Drug

    Alfaxalone

    go.drugbank.com/drugs/DB11371
    ExperimentalVet approved

    It is used in veterinary practice under the trade name Alfaxan, and is licensed for use in both dogs and cats. … Alfaxalone, also known as alphaxalone or alphaxolone, is a neuroactive steroid and general anaesthetic.

  2. Drug

    Melarsomine

    go.drugbank.com/drugs/DB11528
    ExperimentalVet approved

    Melarsomine is a trypanocidal agent marketed by Merial under the trade name Immiticide. … It is the only FDA-approved treatment for adult heartworm infection in dogs, however, is is not approved for use in dogs with late-stage infection.

  3. Drug

    Olenasufligene relduparvovec

    go.drugbank.com/drugs/DB16264
    Investigational

    It is an adeno-associated virus (AAV) vector that delivers a functional copy of the human SGSH gene.[L46671] … Olenasufligene relduparvovec is under investigation in clinical trial NCT03612869 (Study of aavrh10-h.sgsh Gene Therapy in Patients With Mucopolysaccharidosis Type IIIA (MPS IIIA)).

    Synonyms: Dna (recombinant adeno-associated virus 2 vector lys-saf302 human n-sulfoglucosamine sulfohydrolase cdna-specifying)
  4. Drug

    Tandamine

    go.drugbank.com/drugs/DB09192
    Experimental

    Tandamine was researched in 1970s as an antidepressant but was never commercialized. Tandamine is an analog of pirandamine and it acts as a selective serotonin reuptake inhibitor (SSRI).

  5. Drug

    Tunicamycin

    go.drugbank.com/drugs/DB13172
    Experimental

    Tunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. … Tunicamycin blocks N-linked glycosylation (N-glycans) resulting in cell cycle arrest at the G1 phase in human cells. It is used as an experimental tool to induce unfolded protein response.

  6. Drug

    Loprazolam

    go.drugbank.com/drugs/DB13643
    Experimental

    It is a positive modulator of GABA-A receptor that enhances the inhibitory neurotransmission. It is not an FDA-approved drug. … It is indicated for the short-term treatment of insomnia including difficulty in falling asleep and/or frequent nocturnal awakenings.

  7. Drug

    Efineptakin alfa

    go.drugbank.com/drugs/DB16395
    Investigational

    This drug is currently being investigated in the areas of oncology, immunology, and infectious disease. … Compared to endogenous IL-7, NT-I7 is more stable and potent, has a longer half-life, and has better bioavailability.

    Synonyms: NT-I7, Recombinant human IL-7-HYFC
  8. Drug

    Flurbiprofen axetil

    go.drugbank.com/drugs/DB14938
    Investigational

    Flurbiprofen axetil is under investigation in clinical trial NCT02043366 (Effect of Butorphanol Combined With Flurbiprofen Axetil on Preventing Hyperalgesia Induced by Remifentanil in Patients).

  9. Drug

    Dihydromyricetin

    go.drugbank.com/drugs/DB15645
    Investigational

    Dihydromyricetin is under investigation in clinical trial NCT03606694 (Effect of Dihydromirycetin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Type 2 Diabetes Mellitus).

  10. Drug

    Pirepemat

    go.drugbank.com/drugs/DB19165
    Investigational

    Pirepemat is under investigation in clinical trial NCT05258071 (A Clinical Study Evaluating Efficacy of Pirepemat on Falls Frequency in Patients With Parkinson's Disease (PD)).