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Displaying results 951 - 960 of 10000 in total
  1. Drug

    Permethrin

    go.drugbank.com/drugs/DB04930
    ApprovedInvestigational

    A pyrethroid insecticide commonly used in the treatment of lice infestations and scabies. It is a yellow to light orange-brown, low melt-ing solid or viscous liquid.

    Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesSynonyms: (3-Phenoxyphenyl)methyl (±)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate, 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester
  2. Drug

    Alirocumab

    go.drugbank.com/drugs/DB09302
    ApprovedInvestigational

    Alirocumab is a biopharmaceutical that obtained FDA approval in July 2015 as a second line treatment for high cholesterol in adults whose LDL-cholesterol (LDL-C) is not controlled by the combination of … It is a human monoclonal antibody part of the family of the PCSK9 inhibitors which are a novel class of anticholesterol therapeutics. From this family, it was the first agent to receive FDA approval.

    Categories: Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 75MG/ML, PRALUENT SOLUTION FOR INJECTION IN A PRE-FILLED PEN 150 MG/ML
  3. Drug

    Erenumab

    go.drugbank.com/drugs/DB14039
    ApprovedInvestigational

    Erenumab (AMG-334) (INN; trade name Aimovig) is a human monoclonal antibody designed specifically to bind and antagonize the calcitonin gene-related peptide receptor (CGRPR) as a means to prevent migraines … CGRP receptor, which is believed to play a critical role in migraine [L2823].

    Products: Pasurta 70mg/ml Solution for Injection in a Prefilled Syringe, PASURTA® 70MG/ML
  4. Indication

    Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications

    go.drugbank.com/conditions/DBCOND0106269
    Drugs: Dextran
    Synonyms: Venous Thrombosis caused by procedures associated with a high incidence of thromboembolic complications
  5. Drug

    Crotamiton

    go.drugbank.com/drugs/DB00265
    Approved

    Crotamiton is a scabicidal and antipruritic agent available as a cream or lotion for topical use only. It is a colorless to slightly yellowish oil, having a faint amine-like odor.

    Categories: Compounds used in a research, industrial, or household settingProducts: A-Bite Cream, CROTAMITON LOCION AL 10 %
  6. Drug

    Centella asiatica

    go.drugbank.com/drugs/DB14256
    Approved

    Centella asiatica is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Mixtures: MADECASSOL CSynonyms: Luo De Da Whole, Ma Ti Cao Whole
  7. Target

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

    go.drugbank.com/bio_entities/BE0004551
    TargetHumans

    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly ...

    Polypeptides: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
  8. Indication

    Hepatitis C Infections

    go.drugbank.com/conditions/DBCOND0072126
    Drugs: Interferon alfa
    Synonyms: Hep non-A non-B, Hepatitis non-A non-B
  9. Drug

    Somatotropin

    go.drugbank.com/drugs/DB00052
    ApprovedInvestigational

    [A228183, L31508] Synthesized in a strain of _Escherichia coli_, recombinant HGH is a polypeptide hormone that contains 191 amino acid residues with a molecular weight of 22 kDa. … [A228188] Recombinant growth hormone is available as a subcutaneous injection for children and adults under a wide variety of brand names.

    Categories: P-glycoprotein substrates, Cytochrome P-450 CYP1A2 InducersProducts: SciTropin A Solution for Injection 5 mg/1.5 ml, SciTropin A Solution for Injection 10 mg/1.5 ml
  10. Drug

    Polyethylene glycol

    go.drugbank.com/drugs/DB09287
    ApprovedInvestigationalVet approved

    PEGs have a long history of gastroenterology: PEG 3350 is a common over-the-counter osmotic laxative used to relieve occasional constipation. … Polyethylene glycol (PEG) is a synthetic polymer produced via polymerization of ethylene oxide molecules to make joining units of ethylene glycol by an ether linkage.

    Mixtures: Gavilyte-N, DAXTELY FCategories: Compounds used in a research, industrial, or household setting, P-glycoprotein inhibitors